A nanofiltration technique for analyte extraction from complex matrix and surface enhanced Raman spectroscopy based sensing

Onur Durucan (Guest lecturer), Rindzevicius, T. (Other), Michael Stenbæk Schmidt (Other), Ilchenko, O. (Other), Boisen, A. (Other)

Activity: Talks and presentationsConference presentations

Description

Our novel proof-of-concept centrifugal microfluidics sensing platform (Fig.1), allows to perform fast and facile purification (nanofiltration) of the complex sample by incorporating inertial (centrifugal) and capillary forces. Furthermore, integrated in the platform, highly uniform Au capped Si nanopillar (NP) substrates for surface enhanced Raman spectroscopy (SERS) are capable to detect analyte molecules in trace amounts [1]. However, in most of the cases SERS based sensing applications are accompanied with complicated sample manipulation and external purification steps. This can be addressed to various experimental difficulties of SERS based measurements when handling real-life complex samples. Therefore, we believe that combination with the nanofiltration technique would sufficiently increase sensitivity and applicability of SERS based sensors. In addition to that, the nanofiltration of the sample and SERS based sensing of analyte is carried out on the same chip (Au NP surface) which provides robustness to the platform.
Period20 Sep 2017
Held at43rd International conference on Micro and Nano Engineering
Event typeConference
Conference number43
LocationBraga, Portugal
Degree of RecognitionInternational

Keywords

  • SERS
  • Wicking
  • Nanofiltration
  • Centrifugal, Microfluidics
  • Melamine