Variation of translocation efficiency through constriction larger than the particle by Brownian motion

Research output: Research - peer-reviewArticle in proceedings – Annual report year: 2018

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DNA molecules need to wait for entry into the nanopores of sequencers if the molecular length is larger than the pore width. Brownian motion explores diverse configurations randomly and some of them let the molecule pass through the nanopore. On the other hand, ink does not change its color when flowing through a pen where a constriction exists because the pigment particles are smaller than the channel width in the pen. The pigment particles are supposed to follow the streamlines of the dispersant fluid on average. However, we have found that a spherical particle can exhibit different transport efficiency due to Brownian motion when it translocates through a constriction even when the narrower part is still larger than the particle size. In particular, there is a maximum transport efficiency depending on the Péclet number, which is of great importance in the industrial context such as filtration with a huge pressure difference.
Original languageEnglish
Title of host publicationThe proceedings of the JSME annual meeting
Number of pages2
PublisherThe Japan Society of Mechanical Engineers
Publication date2018
Article numberJ2210305
StatePublished - 2018
EventAnnual Meeting of the Japanese Society of Mechanical Engineers - Suita, Japan
Duration: 9 Sep 201812 Sep 2018

Conference

ConferenceAnnual Meeting of the Japanese Society of Mechanical Engineers
CountryJapan
CitySuita
Period09/09/201812/09/2018

    Research areas

  • Brownian motion, Péclet number, Particle, Fluid, Flow
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