The Center for Integrated Molecular Brain Imaging (Cimbi) database

Publication: Research - peer-reviewJournal article – Annual report year: 2015

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DOI

  • Author: Knudsen, Gitte M.

    Copenhagen University Hospital

  • Author: Jensen, Peter S.

    Copenhagen University Hospital

  • Author: Erritzoe, David

    Copenhagen University Hospital, Denmark

  • Author: Baaré, William F. C.

    Copenhagen University Hospital, Denmark

  • Author: Ettrup, Anders

    Copenhagen University Hospital, Denmark

  • Author: Fisher, Patrick M.

    Copenhagen University Hospital, Denmark

  • Author: Gillings, Nic

    Copenhagen University Hospital, Denmark

  • Author: Hansen, Hanne D.

    Copenhagen University Hospital, Denmark

  • Author: Hansen, Lars Kai

    Cognitive Systems, Department of Applied Mathematics and Computer Science , Copenhagen Center for Health Technology, Center, Technical University of Denmark, Richard Petersens Plads, 2800, Kgs. Lyngby, Denmark

  • Author: Hasselbalch, Steen G

    Copenhagen University Hospital, Denmark

  • Author: Henningsson, Susanne

    Copenhagen University Hospital, Denmark

  • Author: Herth, Matthias M

    Copenhagen University Hospital, Denmark

  • Author: Holst, Klaus K

    Copenhagen University Hospital, Denmark

  • Author: Iversen, Pernille

    Copenhagen University Hospital

  • Author: Kessing, Lars V

    Copenhagen University Hospital, Denmark

  • Author: Macoveanu, Julian

    Copenhagen University Hospital, Denmark

  • Author: Madsen, Kathrine Skak

    Copenhagen University Hospital

  • Author: Mortensen, Erik L

    University of Copenhagen, Denmark

  • Author: Nielsen, Finn Årup

    Cognitive Systems, Department of Applied Mathematics and Computer Science , Technical University of Denmark, Richard Petersens Plads, 2800, Kgs. Lyngby, Denmark

  • Author: Paulson, Olaf B.

    Copenhagen University Hospital, Denmark

  • Author: Siebner, Hartwig R.

    Copenhagen University Hospital, Denmark

  • Author: Stenbæk, Dea S.

    Copenhagen University Hospital, Denmark

  • Author: Svarer, Claus

    Copenhagen University Hospital

  • Author: Jernigan, Terry L.

    University of California, United States

  • Author: Strother, Stephen C.

    Rotman Research Institute, Canada

  • Author: Frokjaer, Vibe G.

    Copenhagen University Hospital, Denmark

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We here describe a multimodality neuroimaging containing data from healthy volunteers and patients, acquired within the Lundbeck Foundation Center for Integrated Molecular Brain Imaging (Cimbi) in Copenhagen, Denmark. The data is of particular relevance for neurobiological research questions related to the serotonergic transmitter system with its normative data on the serotonergic subtype receptors 5-HT1A, 5-HT1B, 5-HT2A, and 5-HT4 and the 5-HT transporter (5-HTT), but can easily serve other purposes.

The Cimbi database and Cimbi biobank were formally established in 2008 with the purpose to store the wealth of Cimbi-acquired data in a highly structured and standardized manner in accordance with the regulations issued by the Danish Data Protection Agency as well as to provide a quality-controlled resource for future hypothesis-generating and hypothesis-driven studies. The Cimbi database currently comprises a total of 1100 PET and 1000 structural and functional MRI scans and it holds a multitude of additional data, such as genetic and biochemical data, and scores from 17 self-reported questionnaires and from 11 neuropsychological paper/computer tests.

The database associated Cimbi biobank currently contains blood and in some instances saliva samples from about 500 healthy volunteers and 300 patients with e.g., major depression, dementia, substance abuse, obesity, and impulsive aggression. Data continue to be added to the Cimbi database and biobank.
Original languageEnglish
JournalNeuroimage
Volume124, Part B
Issue numberJanuary 2016
Pages (from-to)1213-1219
ISSN1053-8119
DOIs
StatePublished - 2016
CitationsWeb of Science® Times Cited: 8
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