Synthesis and single crystal X-ray analysis of two griseofulvin metabolites
Publication: Research - peer-review › Journal article – Annual report year: 2010
The two phenols, 6-O-desmethyl griseofulvin and 4-O-desmethyl griseofulvin are metabolites of the antifungal drug griseofulvin. Herein, we present an improved synthesis of the 6-phenol derivative, and an unequivocal proof of both structures by single-crystal X-ray analysis.
| Original language | English |
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| Journal | Tetrahedron Letters |
| Publication date | 2010 |
| Volume | 51 |
| Journal number | 45 |
| Pages | 5881-5882 |
| ISSN | 0040-4039 |
| DOIs | |
| State | Published |
| Citations | Web of Science® Times Cited: 4 |
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Keywords
- Griseofulvin, Metabolites, Synthesis, X-ray structures
ID: 5233871