Publication: Research - peer-review › Article in proceedings – Annual report year: 2011
This paper reports a surface modification of epoxy-based negative photoresist SU-8 for reducing its autofluorescence while enhancing its biofunctionality. By covalently depositing a thin layer of 20 nm Au nanoparticles (AuNPs) onto the SU-8 surface, we found that the AuNPs-coated SU-8 surface is much less fluorescent than the untreated SU-8. Moreover, DNA probes can easily be immobilized on the Au surface and are thermally stable over a wide range of temperature. These improvements will benefit bioanalytical applications such as DNA hybridization and solid-phase PCR (SP-PCR).
|Title of host publication||15th International Conference on Miniaturized Systems for Chemistry and Life Sciences|
|Publisher||Chemical and Biological Microsystems Society|
|State||Published - 2011|
|Event||15th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Seattle, WA, United States|
|Conference||15th International Conference on Miniaturized Systems for Chemistry and Life Sciences|
|Period||02/10/2011 → 06/10/2011|
- DNA Detection, SU-8, Gold Nanoparticles, Autofluorescence, Photoresist
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