Surface Modification of Photoresist SU-8 for Low Autofluorescence and Bioanalytical Applications

Publication: Research - peer-reviewArticle in proceedings – Annual report year: 2011

View graph of relations

This paper reports a surface modification of epoxy-based negative photoresist SU-8 for reducing its autofluorescence while enhancing its biofunctionality. By covalently depositing a thin layer of 20 nm Au nanoparticles (AuNPs) onto the SU-8 surface, we found that the AuNPs-coated SU-8 surface is much less fluorescent than the untreated SU-8. Moreover, DNA probes can easily be immobilized on the Au surface and are thermally stable over a wide range of temperature. These improvements will benefit bioanalytical applications such as DNA hybridization and solid-phase PCR (SP-PCR).
Original languageEnglish
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Publication date2011
Pages1161-1163
ISBN (print)978-0-9798064-4-5
StatePublished

Conference

Conference15th International Conference on Miniaturized Systems for Chemistry and Life Sciences
CountryUnited States
CitySeattle, WA
Period02/10/1106/10/11
Internet addresshttp://www.microtas2011.org/

Keywords

  • DNA Detection, SU-8, Gold Nanoparticles, Autofluorescence, Photoresist
Download as:
Download as PDF
Select render style:
APAAuthorCBEHarvardMLAStandardVancouverShortLong
PDF
Download as HTML
Select render style:
APAAuthorCBEHarvardMLAStandardVancouverShortLong
HTML
Download as Word
Select render style:
APAAuthorCBEHarvardMLAStandardVancouverShortLong
Word

ID: 6322830