Serological response to vaccination against avian influenza in zoo-birds using an inactivated H5N9 vaccine

Publication: Research - peer-reviewJournal article – Annual report year: 2007

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Five hundred and forty birds in three zoos were vaccinated twice against avian influenza with a 6-week interval using an inactivated H5N9 vaccine. Serological response was evaluated by hemagglutination inhibition test 4-6 weeks following the second vaccine administration. 84% of the birds seroconverted, and 76% developed a titre >= 32. The geometric mean titre after vaccination was 137. A significant species variation in response was noted; penguins, pelicans, ducks, geese, herons, Guinea fowl, cranes, cockatiels, lovebirds, and barbets showed very poor response to vaccination, while very high titres and seroconversion rates were seen in flamingos, ibis, rheas, Congo peafowl, black-winged stilts, amazon parrots, and kookaburras.
Original languageEnglish
JournalVaccine
Publication date2007
Volume25
Issue22
Pages4345-4349
ISSN0264-410X
DOIs
StatePublished
CitationsWeb of Science® Times Cited: 16

Keywords

  • exotic birds, H5N9, vaccination, avian influenza
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