Ruthenium-Catalyzed Alkylation of Oxindole with Alcohols

Publication: Research - peer-reviewJournal article – Annual report year: 2009

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An atom-economical and solvent-free catalytic procedure for the mono-3-alkylation of oxindole with alcohols is described. The reaction is mediated by the in situ generated catalyst from RuCl3 center dot xH(2)O and PPh3 in the presence of sodium hydroxide, The reactions proceed in good to excellent yields with a wide range of aromatic, heteroaromatic, and aliphatic alcohols.
Original languageEnglish
JournalJournal of Organic Chemistry
Publication date2009
Volume74
Journal number10
Pages3990-3992
ISSN0022-3263
DOIs
StatePublished
CitationsWeb of Science® Times Cited: 25
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