Robust Market Launch Planning for a Multi- Echelon Pharmaceutical Supply Chain

Publication: Research - peer-reviewArticle in proceedings – Annual report year: 2011

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It is well known, that the pharmaceutical industry is struggling with increasing cost and length of R&D projects. Earnings of a drug drop drastically after patent expiration. Thus, the industry spends much effort on reducing Time-to-Market. In the literature, little attention is given to drug launching activities after the drug has been approved. In this paper, we present a recourse-based stochastic model, which allows for time phasing the market entries to balance the fluctuating demand with the fixed and periodic production of the active pharmaceutical ingredient. The two major risk elements during launch are forecasting inaccuracy and the risk of a required label change from local regulatory authorities. Robust solutions are found by implementing the Robust Optimization framework.
Original languageEnglish
Title of host publication21st European Symposium on Computer Aided Process Engineering
Number of pages2029
Volume1
PublisherElsevier
Publication date2011
Pages935-939
ISBN (print)978-0-444-53895-6
DOIs
StatePublished - 2011
Peer-reviewedYes

Conference

Conference21st European Symposium on Computer Aided Process Engineering
CountryGreece
CityChalkidiki
Period29/05/201101/06/2011
Internet addresshttp://www.escape-21.gr/
NameComputer - Aided Chemical Engineering
Number29
ISSN (Print)1570-7946
CitationsWeb of Science® Times Cited: No match on DOI

Keywords

  • Market Launch Planning, Multi-Echelon Pharmaceutical Supply Chain, Robustness Optimization, Recourse-based stochastic programming
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