Rapid Methods to Estimate Potential Exposure to Semivolatile Organic Compounds in the Indoor Environment

Publication: Research - peer-reviewJournal article – Annual report year: 2012

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Rapid Methods to Estimate Potential Exposure to Semivolatile Organic Compounds in the Indoor Environment. / Little, John C.; Weschler, Charles J.; Nazaroff, William W; Liu, Zhe; Cohen Hubal, Elaine A.

In: Environmental Science & Technology (Washington), Vol. 46, No. 20, 2012, p. 11171-11178.

Publication: Research - peer-reviewJournal article – Annual report year: 2012

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Author

Little, John C.; Weschler, Charles J.; Nazaroff, William W; Liu, Zhe; Cohen Hubal, Elaine A. / Rapid Methods to Estimate Potential Exposure to Semivolatile Organic Compounds in the Indoor Environment.

In: Environmental Science & Technology (Washington), Vol. 46, No. 20, 2012, p. 11171-11178.

Publication: Research - peer-reviewJournal article – Annual report year: 2012

Bibtex

@article{e2bc8447017e456086fa524193e4cbb2,
title = "Rapid Methods to Estimate Potential Exposure to Semivolatile Organic Compounds in the Indoor Environment",
publisher = "American Chemical Society",
author = "Little, {John C.} and Weschler, {Charles J.} and Nazaroff, {William W} and Zhe Liu and {Cohen Hubal}, {Elaine A.}",
year = "2012",
doi = "10.1021/es301088a",
volume = "46",
number = "20",
pages = "11171--11178",
journal = "Environmental Science & Technology (Washington)",
issn = "0013-936X",

}

RIS

TY - JOUR

T1 - Rapid Methods to Estimate Potential Exposure to Semivolatile Organic Compounds in the Indoor Environment

A1 - Little,John C.

A1 - Weschler,Charles J.

A1 - Nazaroff,William W

A1 - Liu,Zhe

A1 - Cohen Hubal,Elaine A.

AU - Little,John C.

AU - Weschler,Charles J.

AU - Nazaroff,William W

AU - Liu,Zhe

AU - Cohen Hubal,Elaine A.

PB - American Chemical Society

PY - 2012

Y1 - 2012

N2 - A systematic and efficient strategy is needed to assess and manage potential risks to human health that arise from the manufacture and use of thousands of chemicals. Among available tools for rapid assessment of large numbers of chemicals, significant gaps are associated with the capability to evaluate exposures that occur indoors. For semivolatile organic compounds (SVOCs), exposure is strongly influenced by the types of products in which these SVOCs occur. We propose methods for obtaining screening-level estimates for two primary SVOC source classes: additives in products used indoors and ingredients in products sprayed or applied to interior surfaces. Accounting for product use, emission characteristics, and the properties of the SVOCs, we estimate exposure via inhalation of SVOCs in the gas-phase, inhalation of SVOCs sorbed to airborne particles, ingestion of SVOCs sorbed to dust, and dermal sorption of SVOCs from the air into the blood. We also evaluate how exposure to the general public will change if chemical substitutions are made. Further development of a comprehensive set of models including the other SVOC-containing products and the other SVOC exposure pathways, together with appropriate methods for estimating or measuring the key parameters (in particular, the gas-phase concentration in equilibrium with the material-phase concentration of the SVOC in the product, or y0), is needed. When combined with rapid toxicity estimates, screening-level exposure estimates can contribute to health-risk-based prioritization of a wide range of chemicals of concern.

AB - A systematic and efficient strategy is needed to assess and manage potential risks to human health that arise from the manufacture and use of thousands of chemicals. Among available tools for rapid assessment of large numbers of chemicals, significant gaps are associated with the capability to evaluate exposures that occur indoors. For semivolatile organic compounds (SVOCs), exposure is strongly influenced by the types of products in which these SVOCs occur. We propose methods for obtaining screening-level estimates for two primary SVOC source classes: additives in products used indoors and ingredients in products sprayed or applied to interior surfaces. Accounting for product use, emission characteristics, and the properties of the SVOCs, we estimate exposure via inhalation of SVOCs in the gas-phase, inhalation of SVOCs sorbed to airborne particles, ingestion of SVOCs sorbed to dust, and dermal sorption of SVOCs from the air into the blood. We also evaluate how exposure to the general public will change if chemical substitutions are made. Further development of a comprehensive set of models including the other SVOC-containing products and the other SVOC exposure pathways, together with appropriate methods for estimating or measuring the key parameters (in particular, the gas-phase concentration in equilibrium with the material-phase concentration of the SVOC in the product, or y0), is needed. When combined with rapid toxicity estimates, screening-level exposure estimates can contribute to health-risk-based prioritization of a wide range of chemicals of concern.

U2 - 10.1021/es301088a

DO - 10.1021/es301088a

JO - Environmental Science & Technology (Washington)

JF - Environmental Science & Technology (Washington)

SN - 0013-936X

IS - 20

VL - 46

SP - 11171

EP - 11178

ER -