TY - BOOK

T1 - Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators

A1 - Beierholm,Anders Ravnsborg

AU - Beierholm,Anders Ravnsborg

PB - Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi

PY - 2011

Y1 - 2011

N2 - This PhD project pertains to the development and <br/>adaptation of a dosimetry system that can be used <br/>to verify the delivery of radiation in modern radiotherapy <br/>modalities involving small radiation fields <br/>and dynamic radiation delivery. <br/>The dosimetry system is based on fibre-coupled <br/>organic scintillators and can be perceived as a well <br/>characterized, independent alternative to the methods <br/>that are in clinical use today. The dosimeter itself <br/>does not require a voltage supply, and is composed <br/>of water equivalent materials. The dosimeter <br/>can be fabricated with a sensitive volume smaller <br/>than a cubic millimeter, which is small enough to <br/>resolve the small radiation fields encountered in <br/>modern radiotherapy. The fast readout of the dosimeter <br/>enables measurements on the same time <br/>scale as the pulsed radiation delivery from the <br/>medical linear accelerators used for treatment. <br/>The dosimetry system, comprising fiber-coupled <br/>organic scintillators and data acquisition hardware, <br/>was developed at the Radiation Research Division <br/>at Risø DTU and tested using clinical x-ray beams <br/>at hospitals in Denmark and abroad. <br/>Measurements of output factors and percentage <br/>depth dose were performed and compared with reference <br/>values and Monte Carlo simulations for static <br/>square radiation fields for standard (4 cm x 4 cm <br/>to 20 cm x 20 cm) and small (down to 0.6 cm x <br/>0.6 cm) field sizes. The accuracy of most of the obtained <br/>measurements was good, agreeing with reference <br/>and simulated dose values to within 2 % <br/>standard deviation for both standard and small <br/>fields. <br/>This thesis concludes that the new pulse-resolved <br/>dosimetry system holds great potential for modern <br/>radiotherapy applications, such as stereotactic <br/>radiotherapy and intensity-modulated radiotherapy.

AB - This PhD project pertains to the development and <br/>adaptation of a dosimetry system that can be used <br/>to verify the delivery of radiation in modern radiotherapy <br/>modalities involving small radiation fields <br/>and dynamic radiation delivery. <br/>The dosimetry system is based on fibre-coupled <br/>organic scintillators and can be perceived as a well <br/>characterized, independent alternative to the methods <br/>that are in clinical use today. The dosimeter itself <br/>does not require a voltage supply, and is composed <br/>of water equivalent materials. The dosimeter <br/>can be fabricated with a sensitive volume smaller <br/>than a cubic millimeter, which is small enough to <br/>resolve the small radiation fields encountered in <br/>modern radiotherapy. The fast readout of the dosimeter <br/>enables measurements on the same time <br/>scale as the pulsed radiation delivery from the <br/>medical linear accelerators used for treatment. <br/>The dosimetry system, comprising fiber-coupled <br/>organic scintillators and data acquisition hardware, <br/>was developed at the Radiation Research Division <br/>at Risø DTU and tested using clinical x-ray beams <br/>at hospitals in Denmark and abroad. <br/>Measurements of output factors and percentage <br/>depth dose were performed and compared with reference <br/>values and Monte Carlo simulations for static <br/>square radiation fields for standard (4 cm x 4 cm <br/>to 20 cm x 20 cm) and small (down to 0.6 cm x <br/>0.6 cm) field sizes. The accuracy of most of the obtained <br/>measurements was good, agreeing with reference <br/>and simulated dose values to within 2 % <br/>standard deviation for both standard and small <br/>fields. <br/>This thesis concludes that the new pulse-resolved <br/>dosimetry system holds great potential for modern <br/>radiotherapy applications, such as stereotactic <br/>radiotherapy and intensity-modulated radiotherapy.

KW - Risø-PhD-85

KW - Risø-PhD-85(EN)

BT - Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators

T3 - Risø-PhD

T3 - en_GB

ER -