Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators

Publication: ResearchPh.D. thesis – Annual report year: 2012

Standard

Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators. / Beierholm, Anders Ravnsborg.

Roskilde : Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi, 2011. (Risø-PhD; No. 85(EN)).

Publication: ResearchPh.D. thesis – Annual report year: 2012

Harvard

Beierholm, AR 2011, Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators. Ph.D. thesis, Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi, Roskilde. Risø-PhD, no. 85(EN)

APA

Beierholm, A. R. (2011). Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators. Roskilde: Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi. (Risø-PhD; No. 85(EN)).

CBE

Beierholm AR 2011. Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators. Roskilde: Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi. (Risø-PhD; No. 85(EN)).

MLA

Beierholm, Anders Ravnsborg Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators Roskilde: Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi. 2011. (Risø-PhD; Journal number 85(EN)).

Vancouver

Beierholm AR. Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators. Roskilde: Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi, 2011. (Risø-PhD; No. 85(EN)).

Author

Beierholm, Anders Ravnsborg / Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators.

Roskilde : Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi, 2011. (Risø-PhD; No. 85(EN)).

Publication: ResearchPh.D. thesis – Annual report year: 2012

Bibtex

@phdthesis{6ef1c3c312624da48c050761e2e2434d,
title = "Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators",
keywords = "Risø-PhD-85, Risø-PhD-85(EN)",
author = "Beierholm, {Anders Ravnsborg}",
year = "2011",
publisher = "Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi",

}

RIS

TY - BOOK

T1 - Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators

AU - Beierholm,Anders Ravnsborg

PY - 2011

Y1 - 2011

N2 - This PhD project pertains to the development and adaptation of a dosimetry system that can be used to verify the delivery of radiation in modern radiotherapy modalities involving small radiation fields and dynamic radiation delivery. The dosimetry system is based on fibre-coupled organic scintillators and can be perceived as a well characterized, independent alternative to the methods that are in clinical use today. The dosimeter itself does not require a voltage supply, and is composed of water equivalent materials. The dosimeter can be fabricated with a sensitive volume smaller than a cubic millimeter, which is small enough to resolve the small radiation fields encountered in modern radiotherapy. The fast readout of the dosimeter enables measurements on the same time scale as the pulsed radiation delivery from the medical linear accelerators used for treatment. The dosimetry system, comprising fiber-coupled organic scintillators and data acquisition hardware, was developed at the Radiation Research Division at Risø DTU and tested using clinical x-ray beams at hospitals in Denmark and abroad. Measurements of output factors and percentage depth dose were performed and compared with reference values and Monte Carlo simulations for static square radiation fields for standard (4 cm x 4 cm to 20 cm x 20 cm) and small (down to 0.6 cm x 0.6 cm) field sizes. The accuracy of most of the obtained measurements was good, agreeing with reference and simulated dose values to within 2 % standard deviation for both standard and small fields. This thesis concludes that the new pulse-resolved dosimetry system holds great potential for modern radiotherapy applications, such as stereotactic radiotherapy and intensity-modulated radiotherapy.

AB - This PhD project pertains to the development and adaptation of a dosimetry system that can be used to verify the delivery of radiation in modern radiotherapy modalities involving small radiation fields and dynamic radiation delivery. The dosimetry system is based on fibre-coupled organic scintillators and can be perceived as a well characterized, independent alternative to the methods that are in clinical use today. The dosimeter itself does not require a voltage supply, and is composed of water equivalent materials. The dosimeter can be fabricated with a sensitive volume smaller than a cubic millimeter, which is small enough to resolve the small radiation fields encountered in modern radiotherapy. The fast readout of the dosimeter enables measurements on the same time scale as the pulsed radiation delivery from the medical linear accelerators used for treatment. The dosimetry system, comprising fiber-coupled organic scintillators and data acquisition hardware, was developed at the Radiation Research Division at Risø DTU and tested using clinical x-ray beams at hospitals in Denmark and abroad. Measurements of output factors and percentage depth dose were performed and compared with reference values and Monte Carlo simulations for static square radiation fields for standard (4 cm x 4 cm to 20 cm x 20 cm) and small (down to 0.6 cm x 0.6 cm) field sizes. The accuracy of most of the obtained measurements was good, agreeing with reference and simulated dose values to within 2 % standard deviation for both standard and small fields. This thesis concludes that the new pulse-resolved dosimetry system holds great potential for modern radiotherapy applications, such as stereotactic radiotherapy and intensity-modulated radiotherapy.

KW - Risø-PhD-85

KW - Risø-PhD-85(EN)

M3 - Ph.D. thesis

BT - Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators

PB - Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi

ER -