Pulse-resolved radiotherapy dosimetry using fiber-coupled organic scintillators

Publication: ResearchPh.D. thesis – Annual report year: 2012

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This PhD project pertains to the development and
adaptation of a dosimetry system that can be used
to verify the delivery of radiation in modern radiotherapy
modalities involving small radiation fields
and dynamic radiation delivery.
The dosimetry system is based on fibre-coupled
organic scintillators and can be perceived as a well
characterized, independent alternative to the methods
that are in clinical use today. The dosimeter itself
does not require a voltage supply, and is composed
of water equivalent materials. The dosimeter
can be fabricated with a sensitive volume smaller
than a cubic millimeter, which is small enough to
resolve the small radiation fields encountered in
modern radiotherapy. The fast readout of the dosimeter
enables measurements on the same time
scale as the pulsed radiation delivery from the
medical linear accelerators used for treatment.
The dosimetry system, comprising fiber-coupled
organic scintillators and data acquisition hardware,
was developed at the Radiation Research Division
at Risø DTU and tested using clinical x-ray beams
at hospitals in Denmark and abroad.
Measurements of output factors and percentage
depth dose were performed and compared with reference
values and Monte Carlo simulations for static
square radiation fields for standard (4 cm x 4 cm
to 20 cm x 20 cm) and small (down to 0.6 cm x
0.6 cm) field sizes. The accuracy of most of the obtained
measurements was good, agreeing with reference
and simulated dose values to within 2 %
standard deviation for both standard and small
fields.
This thesis concludes that the new pulse-resolved
dosimetry system holds great potential for modern
radiotherapy applications, such as stereotactic
radiotherapy and intensity-modulated radiotherapy.
Original languageEnglish
Publication date2011
Place of publicationRoskilde
PublisherDanmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi
ISBN (electronic)978-87-550-3935-3
StatePublished
NameRisø-PhD
Number85(EN)

Keywords

  • Risø-PhD-85, Risø-PhD-85(EN)
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