Nucleotide Metabolism

Publication: Research - peer-reviewBook chapter – Annual report year: 2011

Standard

Nucleotide Metabolism. / Martinussen, Jan; Willemoës, M.; Kilstrup, Mogens.

Comprehensive Biotechnology. ed. / Murray Moo-Young. Vol. 1 2. ed. Elsevier Science, 2011. p. 91-107.

Publication: Research - peer-reviewBook chapter – Annual report year: 2011

Harvard

Martinussen, J, Willemoës, M & Kilstrup, M 2011, 'Nucleotide Metabolism'. in M Moo-Young (ed.), Comprehensive Biotechnology. 2 edn, vol. 1, Elsevier Science, pp. 91-107.

APA

Martinussen, J., Willemoës, M., & Kilstrup, M. (2011). Nucleotide Metabolism. In M. Moo-Young (Ed.), Comprehensive Biotechnology. (2 ed., Vol. 1, pp. 91-107). Elsevier Science.

CBE

Martinussen J, Willemoës M, Kilstrup M. 2011. Nucleotide Metabolism. Moo-Young M, editor. In Comprehensive Biotechnology. 2 ed. Elsevier Science. pp. 91-107.

MLA

Martinussen, Jan, M. Willemoës, and Mogens Kilstrup "Nucleotide Metabolism". Moo-Young, Murray (editors). Comprehensive Biotechnology. 2 udg., Elsevier Science. 2011. 91-107.

Vancouver

Martinussen J, Willemoës M, Kilstrup M. Nucleotide Metabolism. In Moo-Young M, editor, Comprehensive Biotechnology. 2 ed. Vol. 1. Elsevier Science. 2011. p. 91-107.

Author

Martinussen, Jan; Willemoës, M.; Kilstrup, Mogens / Nucleotide Metabolism.

Comprehensive Biotechnology. ed. / Murray Moo-Young. Vol. 1 2. ed. Elsevier Science, 2011. p. 91-107.

Publication: Research - peer-reviewBook chapter – Annual report year: 2011

Bibtex

@inbook{18ea362038d04f2da403a41ab8b2b531,
title = "Nucleotide Metabolism",
publisher = "Elsevier Science",
author = "Jan Martinussen and M. Willemoës and Mogens Kilstrup",
year = "2011",
editor = "Murray Moo-Young",
volume = "1",
edition = "2",
isbn = "978-0-08-088504-9",
pages = "91-107",
booktitle = "Comprehensive Biotechnology",

}

RIS

TY - CHAP

T1 - Nucleotide Metabolism

A1 - Martinussen,Jan

A1 - Willemoës,M.

A1 - Kilstrup,Mogens

AU - Martinussen,Jan

AU - Willemoës,M.

AU - Kilstrup,Mogens

PB - Elsevier Science

PY - 2011

Y1 - 2011

N2 - Metabolic pathways are connected through their utilization of nucleotides as supplier of energy, allosteric effectors, and their role in activation of intermediates. Therefore, any attempt to exploit a given living organism in a biotechnological process will have an impact on nucleotide metabolism and vice versa. Here, we provide an overview of the pyrimidine and purine biosynthesis, the interconversion pathways, the formation of deoxyribonucleotides, and the salvage reactions used in the utilization of exogenous precursors. The enzymatic and genetic regulation of these pathways are addressed. The aim of this article is to provide knowledge of nucleotide metabolism and its regulation to facilitate interpretation of data arising from genetics, proteomics, and transcriptomics in connection with biotechnological processes and beyond.

AB - Metabolic pathways are connected through their utilization of nucleotides as supplier of energy, allosteric effectors, and their role in activation of intermediates. Therefore, any attempt to exploit a given living organism in a biotechnological process will have an impact on nucleotide metabolism and vice versa. Here, we provide an overview of the pyrimidine and purine biosynthesis, the interconversion pathways, the formation of deoxyribonucleotides, and the salvage reactions used in the utilization of exogenous precursors. The enzymatic and genetic regulation of these pathways are addressed. The aim of this article is to provide knowledge of nucleotide metabolism and its regulation to facilitate interpretation of data arising from genetics, proteomics, and transcriptomics in connection with biotechnological processes and beyond.

KW - Nucleotide salvage

KW - ATP

KW - dATP

KW - GTP

KW - Purines

KW - dGTP

KW - Nucleotide biosynthesis

KW - UTP

KW - dCTP

KW - Pyrimidines

KW - dTTP

KW - Nucleotide interconversion

KW - CTP

KW - Regulation of gene expression

UR - http://www.sciencedirect.com/science/referenceworks/9780080885049#ancsec1

SN - 978-0-08-088504-9

VL - 1

BT - Comprehensive Biotechnology

T2 - Comprehensive Biotechnology

A2 - Moo-Young,Murray

ED - Moo-Young,Murray

SP - 91

EP - 107

ER -