Micromechanical sensors for the measurement of biopolymer degradation

Publication: Research - peer-reviewArticle in proceedings – Annual report year: 2011

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We present microcantilever-based sensors for the characterization of biopolymer degradation by enzymes. Thin films of Poly(L-lactide) (PLLA) were spray-coated onto SU-8 cantilevers with well-known material properties and dimensions. The micromechanical sensors were immersed in solutions of proteinase K to investigate enzymatic degradation of PLLA. A decrease of the resonance frequency after immersion indicated degradation of the biopolymer coating and allowed the estimation of the degradation rate at a specific enzyme concentration.
Original languageEnglish
Title of host publicationIEEE 24. International Conference on Micro Electro Mechanical Systems (MEMS)
PublisherIEEE
Publication date2011
ISBN (print)978-1-4244-9632-7
DOIs
StatePublished

Conference

Conference24th International Conference on Micro Electro Mechanical Systems
Number24
CountryMexico
CityCancun
Period23/01/1127/01/11
Internet addresshttp://www.ieee-mems2011.org/
CitationsWeb of Science® Times Cited: No match on DOI

Keywords

  • SU-8 cantilevers, POLY(L-lactide) thin films, Micromechanical sensors, Spray coating, Microcantilever-based sensors, Immersion, Biopolymer degradation, Biopolymer coating, Poteinase K, Enzymes, Resonance frequency
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