Metabolic footprint of Lactobacillus acidophilus NCFM at different pH

Publication: Research - peer-reviewJournal article – Annual report year: 2011

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Lactobacillus acidophilus NCFM is a well known microorganism from the genomic and probiotic point of view. In order to analyze the potential interactions of NCFM with the surrounding environment, in vitro tests with the metabolic footprinting approach were performed. It was found that NCFM increased the concentration of lactic acid, succinic acid, adenine and arginine in the medium. The metabolism of NCFM did not change significantly between pH 5 and 7, suggesting that other environmental factors than pH might have bigger impact on its colonization throughout the gastrointestinal tract.
Original languageEnglish
JournalMetabolomics
Publication date2012
Volume8
Issue2
Pages244-252
ISSN1573-3882
DOIs
StatePublished
CitationsWeb of Science® Times Cited: 2

Keywords

  • Probiotics, LCMS, Lactobacillus acidophilus NCFM, Metabolite footprint, GIT, Metabolomics
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