Measurements of Brownian relaxation of magnetic nanobeads using planar Hall effect bridge sensors

Publication: Research - peer-reviewConference article – Annual report year: 2013

View graph of relations

We compare measurements of the Brownian relaxation response of magnetic nanobeads in suspension using planar Hall effect sensors of cross geometry and a newly proposed bridge geometry. We find that the bridge sensor yields six times as large signals as the cross sensor, which results in a more accurate determination of the hydrodynamic size of the magnetic nanobeads. Finally, the bridge sensor has successfully been used to measure the change in dynamic magnetic response when rolling circle amplified DNA molecules are bound to the magnetic nanobeads. The change is validated by measurements performed in a commercial AC susceptometer. The presented bridge sensor is, thus, a promising component in future lab-on-a-chip biosensors for detection of clinically relevant analytes, including bacterial genomic DNA and proteins.
Original languageEnglish
JournalBiosensors and Bioelectronics
Publication date2013
Volume40
Issue1
Pages147-152
ISSN0956-5663
DOIs
StatePublished
CitationsWeb of Science® Times Cited: 10

Keywords

  • Brownian relaxometry, Magnetorelaxometry, Lab-on-a-chip, Magnetic sensor, Biosensor, Magnetic nanobeads
Download as:
Download as PDF
Select render style:
APAAuthorCBEHarvardMLAStandardVancouverShortLong
PDF
Download as HTML
Select render style:
APAAuthorCBEHarvardMLAStandardVancouverShortLong
HTML
Download as Word
Select render style:
APAAuthorCBEHarvardMLAStandardVancouverShortLong
Word

ID: 23335993