TY - JOUR

T1 - Manipulation of self-assembly amyloid peptide nanotubes by dielectrophoresis (DEP)

A1 - Castillo,Jaime

A1 - Tanzi,Simone

A1 - Dimaki,Maria

A1 - Svendsen,Winnie Edith

AU - Castillo,Jaime

AU - Tanzi,Simone

AU - Dimaki,Maria

AU - Svendsen,Winnie Edith

PB - Wiley - V C H Verlag GmbH & Co. KGaA

PY - 2008

Y1 - 2008

N2 - Self-assembled amyloid peptide nanotubes (SAPNT) were manipulated and immobilized using dielectrophoresis. Micro-patterned electrodes of Au were fabricated by photolithography and lifted off on a silicon dioxide layer. SAPNT were manipulated by adjusting the amplitude and frequency of the applied voltage. The immobilized SAPNT were evaluated by SEM and atomic force microscopy. The conductivity of the immobilized SAPNT was studied by I-V characterization, for both single SAPNT and bundles. This work illustrates a way to manipulate and integrate biological nanostructures into novel bio-nanoassemblies with concrete applications, such as field-effect transistors, microprobes, microarrays, and biosensing devices.

AB - Self-assembled amyloid peptide nanotubes (SAPNT) were manipulated and immobilized using dielectrophoresis. Micro-patterned electrodes of Au were fabricated by photolithography and lifted off on a silicon dioxide layer. SAPNT were manipulated by adjusting the amplitude and frequency of the applied voltage. The immobilized SAPNT were evaluated by SEM and atomic force microscopy. The conductivity of the immobilized SAPNT was studied by I-V characterization, for both single SAPNT and bundles. This work illustrates a way to manipulate and integrate biological nanostructures into novel bio-nanoassemblies with concrete applications, such as field-effect transistors, microprobes, microarrays, and biosensing devices.

KW - Dielectrophoresis

KW - Self-assembly

KW - Bionanotechnology

KW - Peptide nanotubes

U2 - 10.1002/elps.200800260

DO - 10.1002/elps.200800260

JO - Electrophoresis

JF - Electrophoresis

SN - 0173-0835

IS - 24

VL - 29

SP - 5026

EP - 5032

ER -