Malignant lymphoma in a west Indian manatee (Trichechus manatus)

Publication: Research - peer-reviewJournal article – Annual report year: 2005

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We identified a malignant lymphoma infiltrating the lung, liver, kidney, mesenteric lymph nodes, and eye as the cause of death in a male West Indian manatee (Trichechus manatus). Diagnosis was based on gross histopathologic, and immunohistochemical studies. Tissue samples from ten organs were included in a tissue microarray and sections from this array were subjected to immunohistochemical staining. The cytoplasm of the neoplastic lymphocytes identified in six organs was positive for CD3, a marker for T-cell differentiation. The neoplastic cells were negative for CD79 alpha, a marker for B-cell differentiation. The cause of this neoplasm was not determined. This is the first report of malignant lymphoma in the mammal order Sirenia.
Original languageEnglish
JournalJournal of Wildlife Diseases
Publication date2005
Volume41
Issue4
Pages834-838
ISSN0090-3558
StatePublished

Keywords

  • tissue microarray, Trichechus manatus, lymphoma, case history, West Indian manatee
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