Liquid phase chromatography on microchips

Publication: Research - peer-reviewJournal article – Annual report year: 2012

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Liquid phase chromatography on microchips. / Kutter, Jörg Peter.

In: Journal of Chromatography A, Vol. 1221, 2012, p. 72-82.

Publication: Research - peer-reviewJournal article – Annual report year: 2012

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Author

Kutter, Jörg Peter / Liquid phase chromatography on microchips.

In: Journal of Chromatography A, Vol. 1221, 2012, p. 72-82.

Publication: Research - peer-reviewJournal article – Annual report year: 2012

Bibtex

@article{ad2f5aa3e9644a58b0855f8978c55c2e,
title = "Liquid phase chromatography on microchips",
keywords = "Lab-on-a-chip, Liquid chromatography, Review, Miniaturization, Microchips",
author = "Kutter, {Jörg Peter}",
year = "2012",
doi = "10.1016/j.chroma.2011.10.044",
volume = "1221",
pages = "72--82",
journal = "Journal of Chromatography A",
issn = "00219673",

}

RIS

TY - JOUR

T1 - Liquid phase chromatography on microchips

A1 - Kutter,Jörg Peter

AU - Kutter,Jörg Peter

PY - 2012

Y1 - 2012

N2 - Over the past twenty years, the field of microfluidics has emerged providing one of the main enabling technologies to realize miniaturized chemical analysis systems, often referred to as micro-Total Analysis Systems (uTAS), or, more generally, Lab-on-a-Chip Systems (LOC) [1,2]. While microfluidics was driven forward a lot from the engineering side, especially with respect to ink jet and dispensing technology, the initial push and interest from the analytical chemistry community was through the desire to develop miniaturized sensors, detectors, and, very early on, separation systems. The initial almost explosive development of, in particular, chromatographic separation systems on microchips, has, however, slowed down in recent years. This review takes a closer, critical look at how liquid phase chromatography has been implemented in miniaturized formats over the past several years, what is important to keep in mind when developing or working with separations in a miniaturized format, and what challenges and pitfalls remain.

AB - Over the past twenty years, the field of microfluidics has emerged providing one of the main enabling technologies to realize miniaturized chemical analysis systems, often referred to as micro-Total Analysis Systems (uTAS), or, more generally, Lab-on-a-Chip Systems (LOC) [1,2]. While microfluidics was driven forward a lot from the engineering side, especially with respect to ink jet and dispensing technology, the initial push and interest from the analytical chemistry community was through the desire to develop miniaturized sensors, detectors, and, very early on, separation systems. The initial almost explosive development of, in particular, chromatographic separation systems on microchips, has, however, slowed down in recent years. This review takes a closer, critical look at how liquid phase chromatography has been implemented in miniaturized formats over the past several years, what is important to keep in mind when developing or working with separations in a miniaturized format, and what challenges and pitfalls remain.

KW - Lab-on-a-chip

KW - Liquid chromatography

KW - Review

KW - Miniaturization

KW - Microchips

U2 - 10.1016/j.chroma.2011.10.044

DO - 10.1016/j.chroma.2011.10.044

JO - Journal of Chromatography A

JF - Journal of Chromatography A

SN - 00219673

VL - 1221

SP - 72

EP - 82

ER -