TY - JOUR

T1 - Knowledge engineering for health: A new discipline required to bridge the “ICT gap” between research and healthcare

A1 - Beck,Tim

A1 - Gollapudi,Sirisha

A1 - Brunak,Søren

A1 - Graf,Norbert

A1 - Lemke,Heinz U.

A1 - Dash,Debasis

A1 - Buchan,Iain

A1 - Díaz,Carlos

A1 - Sanz,Ferran

A1 - Brookes,Anthony J.

AU - Beck,Tim

AU - Gollapudi,Sirisha

AU - Brunak,Søren

AU - Graf,Norbert

AU - Lemke,Heinz U.

AU - Dash,Debasis

AU - Buchan,Iain

AU - Díaz,Carlos

AU - Sanz,Ferran

AU - Brookes,Anthony J.

PB - John/Wiley & Sons, Inc. John/Wiley & Sons Ltd.

PY - 2012

Y1 - 2012

N2 - Despite vast amount of money and research being channeled toward biomedical research, relatively little impact has been made on routine clinical practice. At the heart of this failure is the information and communication technology “chasm” that exists between research and healthcare. A new focus on “knowledge engineering for health” is needed to facilitate knowledge transmission across the research–healthcare gap. This discipline is required to engineer the bidirectional flow of data: processing research data and knowledge to identify clinically relevant advances and delivering these into healthcare use; conversely, making outcomes from the practice of medicine suitably available for use by the research community. This system will be able to self‐optimize in that outcomes for patients treated by decisions that were based on the latest research knowledge will be fed back to the research world. A series of meetings, culminating in the “I‐Health 2011” workshop, have brought together interdisciplinary experts to map the challenges and requirements for such a system. Here, we describe the main conclusions from these meetings. An “I4Health” interdisciplinary network of experts now exists to promote the key aims and objectives, namely “integrating and interpreting information for individualized healthcare,” by developing the “knowledge engineering for health” domain. Hum Mutat 33:797–802, 2012. © 2012 Wiley Periodicals, Inc.

AB - Despite vast amount of money and research being channeled toward biomedical research, relatively little impact has been made on routine clinical practice. At the heart of this failure is the information and communication technology “chasm” that exists between research and healthcare. A new focus on “knowledge engineering for health” is needed to facilitate knowledge transmission across the research–healthcare gap. This discipline is required to engineer the bidirectional flow of data: processing research data and knowledge to identify clinically relevant advances and delivering these into healthcare use; conversely, making outcomes from the practice of medicine suitably available for use by the research community. This system will be able to self‐optimize in that outcomes for patients treated by decisions that were based on the latest research knowledge will be fed back to the research world. A series of meetings, culminating in the “I‐Health 2011” workshop, have brought together interdisciplinary experts to map the challenges and requirements for such a system. Here, we describe the main conclusions from these meetings. An “I4Health” interdisciplinary network of experts now exists to promote the key aims and objectives, namely “integrating and interpreting information for individualized healthcare,” by developing the “knowledge engineering for health” domain. Hum Mutat 33:797–802, 2012. © 2012 Wiley Periodicals, Inc.

U2 - 10.1002/humu.22066

DO - 10.1002/humu.22066

JO - Human Mutation

JF - Human Mutation

SN - 1059-7794

IS - 5

VL - 33

SP - 797

EP - 802

ER -