Integrating phenotypic data from electronic patient records with molecular level systems biology : Abstract of invited lecture
Publication: Research - peer-review › Conference article – Annual report year: 2011
Electronic patient records remain a rather unexplored, but potentially
rich data source for discovering correlations between diseases.
We describe a general approach for gathering phenotypic
descriptions of patients from medical records in a systematic and
non-cohort dependent manner. By extracting phenotype information
from the free-text in such records we demonstrate that we
can extend the information contained in the structured record
data, and use it for producing fine-grained patient stratification
and disease co-occurrence statistics. The approach uses a dictionary
based on the International Classification of Disease ontology
and is therefore in principle language independent. As a use
case we show how records from a Danish psychiatric hospital
lead to the identification of disease correlations, which subsequently
are mapped to systems biology frameworks.
| Original language | English |
|---|---|
| Journal | FEBS JOURNAL |
| Publication date | 2011 |
| Volume | 278 |
| Journal number | Suppl. s1 |
| Pages | 27 |
| ISSN | 1742-464X |
| DOIs | |
| State | Published |
Conference
| Conference | FEBS Congress : Biochemistry for Tomorrows Medicine |
|---|---|
| Number | 36 |
| City | Torino, Italy |
| Period | 01-01-11 → … |
| Citations | Web of Science® Times Cited: No match on DOI |
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