Improved detection and biopsy of solid liver lesions using pulse-inversion ultrasound scanning and contrast agent infusion

Publication: Research - peer-reviewJournal article – Annual report year: 2002

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Improved detection and biopsy of solid liver lesions using pulse-inversion ultrasound scanning and contrast agent infusion. / Skjoldbye, B.; Pedersen, Morten Høgholm; Struckmann, J.; Burcharth, F.; Larsen, T.

In: Ultrasound in Medicine & Biology, Vol. 28, No. 4, 2002, p. 439-444.

Publication: Research - peer-reviewJournal article – Annual report year: 2002

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Skjoldbye, B.; Pedersen, Morten Høgholm; Struckmann, J.; Burcharth, F.; Larsen, T. / Improved detection and biopsy of solid liver lesions using pulse-inversion ultrasound scanning and contrast agent infusion.

In: Ultrasound in Medicine & Biology, Vol. 28, No. 4, 2002, p. 439-444.

Publication: Research - peer-reviewJournal article – Annual report year: 2002

Bibtex

@article{c0c689e62a314b039f6cfeb3177ce62c,
title = "Improved detection and biopsy of solid liver lesions using pulse-inversion ultrasound scanning and contrast agent infusion",
publisher = "Elsevier Inc.",
author = "B. Skjoldbye and Pedersen, {Morten Høgholm} and J. Struckmann and F. Burcharth and T. Larsen",
year = "2002",
doi = "10.1016/S0301-5629(02)00484-2",
volume = "28",
number = "4",
pages = "439--444",
journal = "Ultrasound in Medicine & Biology",
issn = "0301-5629",

}

RIS

TY - JOUR

T1 - Improved detection and biopsy of solid liver lesions using pulse-inversion ultrasound scanning and contrast agent infusion

A1 - Skjoldbye,B.

A1 - Pedersen,Morten Høgholm

A1 - Struckmann,J.

A1 - Burcharth,F.

A1 - Larsen,T.

AU - Skjoldbye,B.

AU - Pedersen,Morten Høgholm

AU - Struckmann,J.

AU - Burcharth,F.

AU - Larsen,T.

PB - Elsevier Inc.

PY - 2002

Y1 - 2002

N2 - The purpose of this study was to assess the ability of pulse-inversion ultrasound (US) scanning (PIUS), combined with an IV contrast agent, to detect malignant liver lesions and its impact on patient management (resectability). Additionally, to determine the feasibility of US-guided biopsy of new PIUS-findings at the same session. A total of 30 patients with known or clinically suspected cancer underwent conventional B-mode scanning and PIUS with IV-administered contrast agent. The number of liver metastases in the right and the left liver lobe, respectively, was recorded. All patients with additional findings by PIUS underwent US-guided biopsy. PIUS provided additional information in 18 patients (60%); of these, 13 (43%) had additional metastases. Of 19 patients found resectable by conventional US, 9 (47%) were considered inoperable using PIUS supported by biopsies. Biopsies of additional findings were performed in 17 of 18 patients. All biopsies of additional findings confirmed malignancy. PIUS with an IV contrast agent increased the ability to detect liver metastases compared to conventional US scanning. The technique had a high impact on patient management. The results showed that PIUS-guided biopsy was possible. PIUS with IV contrast will undoubtedly become an important diagnostic tool in the evaluation of patients with metastatic liver disease. (E-mail:bos@dadlnet.dk)

AB - The purpose of this study was to assess the ability of pulse-inversion ultrasound (US) scanning (PIUS), combined with an IV contrast agent, to detect malignant liver lesions and its impact on patient management (resectability). Additionally, to determine the feasibility of US-guided biopsy of new PIUS-findings at the same session. A total of 30 patients with known or clinically suspected cancer underwent conventional B-mode scanning and PIUS with IV-administered contrast agent. The number of liver metastases in the right and the left liver lobe, respectively, was recorded. All patients with additional findings by PIUS underwent US-guided biopsy. PIUS provided additional information in 18 patients (60%); of these, 13 (43%) had additional metastases. Of 19 patients found resectable by conventional US, 9 (47%) were considered inoperable using PIUS supported by biopsies. Biopsies of additional findings were performed in 17 of 18 patients. All biopsies of additional findings confirmed malignancy. PIUS with an IV contrast agent increased the ability to detect liver metastases compared to conventional US scanning. The technique had a high impact on patient management. The results showed that PIUS-guided biopsy was possible. PIUS with IV contrast will undoubtedly become an important diagnostic tool in the evaluation of patients with metastatic liver disease. (E-mail:bos@dadlnet.dk)

UR - http://www.oersted.dtu.dk/publications/p.php?46

U2 - 10.1016/S0301-5629(02)00484-2

DO - 10.1016/S0301-5629(02)00484-2

JO - Ultrasound in Medicine & Biology

JF - Ultrasound in Medicine & Biology

SN - 0301-5629

IS - 4

VL - 28

SP - 439

EP - 444

ER -