Publication: Research - peer-review › Journal article – Annual report year: 2012
The immune epitope database analysis resource (IEDB-AR: http://tools.iedb.org) is a collection of tools for prediction and analysis of molecular targets of T- and B-cell immune responses (i.e. epitopes). Since its last publication in the NAR webserver issue in 2008, a new generation of peptide:MHC binding and T-cell epitope predictive tools have been added. As validated by different labs and in the first international competition for predicting peptide:MHC-I binding, their predictive performances have improved considerably. In addition, a new B-cell epitope prediction tool was added, and the homology mapping tool was updated to enable mapping of discontinuous epitopes onto 3D structures. Furthermore, to serve a wider range of users, the number of ways in which IEDB-AR can be accessed has been expanded. Specifically, the predictive tools can be programmatically accessed using a web interface and can also be downloaded as software packages.
|Citations||Web of Science® Times Cited: 98|
- immune epitope database analysis resource, immune response, MHC-I, MHC-II, peptide, 00530, General biology - Information, documentation, retrieval and computer applications, 02506, Cytology - Animal, 10064, Biochemistry studies - Proteins, peptides and amino acids, 15002, Blood - Blood and lymph studies, 15004, Blood - Blood cell studies, 34502, Immunology - General and methods, Chemical Coordination and Homeostasis, Computational Biology, B-cell immune system, blood and lymphatics, T-cell immune system, blood and lymphatics, computer software package computer software, epitope prediction tool mathematical and computer techniques, homology mapping tool mathematical and computer techniques, Computer Applications, Immune System
No data available