Mining for associations between text and brain activation in a functional neuroimaging database

Research output: Research - peer-reviewJournal article – Annual report year: 2004

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We describe a method for mining a neuroimaging database for associations between text and brain locations. The objective is to discover association rules between words indicative of cognitive function as described in abstracts of neuroscience papers and sets of reported stereotactic Talairach coordinates. We invoke a simple probabilistic framework in which kernel density estimates are used to model distributions of brain activation foci conditioned on words in a given abstract. The principal associations are found in the joint probability density between words and voxels. We show that the statistically motivated associations are well aligned with general neuroscientific knowledge.
Original languageEnglish
JournalNeuroinformatics
Volume2
Issue number4
Pages (from-to)369-379
ISSN1539-2791
StatePublished - 2004

    Research areas

  • data mining, meta-analysis, information storage and retrieval, databases, brain mapping, magnetic resonance imaging, data interpretation, neuroirnaging, positron-emission tomography, statistical
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