High-throughput automated system for statistical biosensing employing microcantilevers arrays

Publication: Research - peer-reviewArticle in proceedings – Annual report year: 2011

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In this paper we present a completely new and fully automated system for parallel microcantilever-based biosensing. Our platform is able to monitor simultaneously the change of resonance frequency (dynamic mode), of deflection (static mode), and of surface roughness of hundreds of cantilevers in a very short time over multiple biochemical reactions. We have proven that our system is capable to measure 900 independent microsensors in less than a second. Here, we report statistical biosensing results performed over a haptens-antibody assay, where complete characterization of the biochemical binding on the cantilever surfaces is obtained with higher accuracy than standard optical lever-based setups.
Original languageEnglish
Title of host publicationIEEE 24. International Conference on Micro Electro Mechanical Systems
PublisherIEEE
Publication date2011
Pages877-880
ISBN (print)978-1-4244-9632-7
DOIs
StatePublished

Conference

Conference24th International Conference on Micro Electro Mechanical Systems
Number24
CountryMexico
CityCancun
Period23/01/1127/01/11
Internet addresshttp://www.ieee-mems2011.org/
CitationsWeb of Science® Times Cited: No match on DOI

Keywords

  • Surface roughness, Measurement by laser beam, Surface treatment, Resonant frequency, Optical sensors, Laser beams
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