• Author: Tam, L.T.

    Hanoi University of Science and Technology, Viet Nam

  • Author: Dinh, N. X.

    Hanoi University of Science and Technology, Viet Nam

  • Author: Cuong, N. V.

    Hanoi University of Science and Technology, Viet Nam

  • Author: Quy, N. V.

    Hanoi University of Science and Technology, Viet Nam

  • Author: Huy, T. Q.

    National Institute of Hygiene and Epidemiology, Viet Nam

  • Author: Ngo, D. T.

    University of Manchester, United Kingdom

  • Author: Mølhave, Kristian

    Molecular Windows, Department of Micro- and Nanotechnology, Technical University of Denmark, Ørsteds Plads, 2800, Kgs. Lyngby, Denmark

  • Author: Le, A. T.

    Hanoi University of Science and Technology, Viet Nam

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In this work, a multi-functional hybrid system consisting of graphene oxide and silver nanoparticles (GO-Ag NPs) was successfully synthesized by using a two-step chemical process. We firstly demonstrated noticeable bactericidal ability of the GO-Ag hybrid system. We provide more chemo-physical evidence explaining the antibacterial behavior of GO-Ag nanohybrid against Gram-negative Escherichia Coli and Gram-positive Staphylococcus aureus in light of ultrastructural damage analyses and Ag1+ ions release rate onto the cells/medium. A further understanding of the mode of antimicrobial action is very important for designing and developing advanced antimicrobial systems. Secondly, we have also demonstrated that the GO-Ag nanohybrid material could be used as a potential surface enhanced Raman scattering (SERS) substrate to detect and quantify organic dyes, e.g., methylene blue (MB), in aqueous media. Our findings revealed that the GO-Ag hybrid system showed better SERS performance of MB detection than that of pure Ag-NPs. MB could be detected at a concentration as low as 1 ppm. The GO-Ag-based SERS platform can be effectively used to detect trace concentrations of various types of organic dyes in aqueous media. With the aforementioned properties, the GO-Ag hybrid system is found to be very promising as a multi-functional material for advanced biomedicine and environmental monitoring applications.
Original languageEnglish
JournalJournal of Electronic Materials
Issue number10
Pages (from-to)5321-5333
Number of pages13
StatePublished - 2016
CitationsWeb of Science® Times Cited: 5


  • GO-Ag nanohybrid, Bactericidal, Electron microscopy, MB detection, Surface enhanced Raman scattering
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