Publication: Research - peer-review › Conference article – Annual report year: 2004
A method to generate strongly polarized nuclear spins in solution has been developed, using Dynamic Nuclear Polarization (DNP) at a temperature of 1.2K, and at a field of 3.354T, corresponding to an electron spin resonance frequency of 94GHz. Trityl radicals are used to directly polarize 13C and other low-γ nuclei. Subsequent to the DNP process, the solid sample is dissolved rapidly with a warm solvent to create a solution of molecules with highly polarized nuclear spins. Two main applications are proposed: high-resolution liquid state NMR with enhanced sensitivity, and the use of the hyperpolarized solution as an MR imaging agent.
|Journal||Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment|
|State||Published - 2004|
|Event||9th International Workshop on Polarized Solid Targets and Techniques - Bad Honnef, Germany|
|Conference||9th International Workshop on Polarized Solid Targets and Techniques|
|Period||27/10/2003 → 29/10/2003|
|Citations||Web of Science® Times Cited: 92|
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