Publication: Research - peer-review › Journal article – Annual report year: 2011
In this paper, we demonstrate the design of a virtually alignment‐free optical setup for use with microfluidic applications involving a layered glass/SU‐8/PDMS (polydimethylsiloxane) chip. We show how inexpensive external lenses combined with carefully designed on‐chip lenses can be used to couple light from a bulk beam to on‐chip waveguides and back into a bulk beam again. Using this setup, as much as 20% of the light coming from the source can be retrieved after passing through the on‐chip waveguides. The proposed setup is based on a pin‐aided alignment system that makes it possible to change chips in the optical train in only a few seconds with a standard deviation of about 2% in the transmitted power. Furthermore, we demonstrate how these optical setups can be combined with microfluidics to create an on‐chip flow cytometer enabling detection and counting of polystyrene particles down to 1 μm at a rate of 100 Hz.
|Citations||Web of Science® Times Cited: No match on DOI|
- Waveguides, Lenses, Light coupling, Alignment‐free, Cytometry