TY - JOUR

T1 - Experimental investigation of new manufacturing process chains to create micro-metal structures on polymer substrates for lab-on-chip sensors

A1 - Calaon,Matteo

A1 - Islam,Aminul

A1 - Hansen,Hans Nørgaard

A1 - Ravn,Christian

AU - Calaon,Matteo

AU - Islam,Aminul

AU - Hansen,Hans Nørgaard

AU - Ravn,Christian

PB - Springer U K

PY - 2012

Y1 - 2012

N2 - Over the last two decades, lab-on-a-chip devices have emerged as a leading technology for life sciences, drug development, medical diagnostics, food safety, agricultural and environmental monitoring. The conventional methods used nowadays to manufacture these micro- and nano-functional surface topography are very expensive, and they do not fit the requirements for industrial production. In particular, we report an experimental investigation to link technologies as structuring process and replication processes by establishing through the proposed low-cost-based approaches new manufacturing process chains to process non-silicon materials devices, which integrate sub-μ periodic structures. Moreover, we introduce a prototype of new testing equipment working in a non-clean environment based on photolithographic procedures. μ-trenches with feature size in the order of 10 μm are integrated on cyclic olefin co-polymer substrates. The achievements authorize to consider the proposed process chain a valid option to fabricate structured surface topography in the sub-μ range for biological applications.

AB - Over the last two decades, lab-on-a-chip devices have emerged as a leading technology for life sciences, drug development, medical diagnostics, food safety, agricultural and environmental monitoring. The conventional methods used nowadays to manufacture these micro- and nano-functional surface topography are very expensive, and they do not fit the requirements for industrial production. In particular, we report an experimental investigation to link technologies as structuring process and replication processes by establishing through the proposed low-cost-based approaches new manufacturing process chains to process non-silicon materials devices, which integrate sub-μ periodic structures. Moreover, we introduce a prototype of new testing equipment working in a non-clean environment based on photolithographic procedures. μ-trenches with feature size in the order of 10 μm are integrated on cyclic olefin co-polymer substrates. The achievements authorize to consider the proposed process chain a valid option to fabricate structured surface topography in the sub-μ range for biological applications.

KW - Replication technology

KW - Structured surface texture

KW - Polymer metallisation

KW - Micro-manufacturing

U2 - 10.1007/s00170-011-3468-2

DO - 10.1007/s00170-011-3468-2

JO - International Journal of Advanced Manufacturing Technology

JF - International Journal of Advanced Manufacturing Technology

SN - 0268-3768

IS - 1-4

VL - 59

SP - 101

EP - 109

ER -