Entrapment of Radionuclides in Nanoparticle Compositions

Publication: ResearchPatent – Annual report year: 2012

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@misc{d6f800315dec405c9a5eaf54632ae77d,
title = "Entrapment of Radionuclides in Nanoparticle Compositions",
author = "Andresen, {Thomas Lars} and Petersen, {Anncatrine Luisa} and Henriksen, {Jonas Rosager} and Palle Rasmussen and Andreas kjær",
note = "DTU reference nummer: 92555-10; WO2012079582; A61K47/28",
year = "2012",
type = "Patent <importModel: PatentImportModel>",

}

RIS

TY - PAT

T1 - Entrapment of Radionuclides in Nanoparticle Compositions

A1 - Andresen,Thomas Lars

A1 - Petersen,Anncatrine Luisa

A1 - Henriksen,Jonas Rosager

A1 - Rasmussen,Palle

A1 - kjær,Andreas

AU - Andresen,Thomas Lars

AU - Petersen,Anncatrine Luisa

AU - Henriksen,Jonas Rosager

AU - Rasmussen,Palle

AU - kjær,Andreas

PY - 2012

Y1 - 2012

N2 - The present invention is directed to the technical field of imaging compositions useful for diagnosing cancer and other diseases in a subject. In particular, the invention relates to a class of diagnostic compounds comprising a novel liposome composition with encapsulated metal entities such as radionuclides,for example 61Cu and 64Cu copper isotopes. The invention further relates to a novel method for loading delivery systems, such as liposome compositions, with metal entities such as radionuclides, and the use of liposomes for targeted diagnosis and treatment of a target site, such as cancerous tissue and, in general, pathological conditions associated with leaky blood vessels. The present invention provides a new diagnostic tool for the utilization of positron emission tomography (PET) imaging technique.

AB - The present invention is directed to the technical field of imaging compositions useful for diagnosing cancer and other diseases in a subject. In particular, the invention relates to a class of diagnostic compounds comprising a novel liposome composition with encapsulated metal entities such as radionuclides,for example 61Cu and 64Cu copper isotopes. The invention further relates to a novel method for loading delivery systems, such as liposome compositions, with metal entities such as radionuclides, and the use of liposomes for targeted diagnosis and treatment of a target site, such as cancerous tissue and, in general, pathological conditions associated with leaky blood vessels. The present invention provides a new diagnostic tool for the utilization of positron emission tomography (PET) imaging technique.

M1 - WO2012079582

Y2 - 2012/06/21

ER -