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Random and systematic errors in case–control studies calculating the injury risk of driving under the influence of psychoactive substances. / Houwing, Sjoerd; Hagenzieker, Marjan; Mathijssen, René P.M.; Legrand, Sara-Ann; Verstraete, Alain G.; Hels, Tove; Bernhoft, Inger Marie; Simonsen, Kirsten Wiese; Lillsunde, Pirjo; Favretto, Donata; Ferrara, Santo D.; Caplinskiene, Marija; Movig, Kris L.L.; Brookhuis, Karel A.

In: Accident Analysis & Prevention, Vol. 52, 2013, p. 144-153.

Publication: Research - peer-reviewJournal article – Annual report year: 2012

Harvard

Houwing, S, Hagenzieker, M, Mathijssen, RPM, Legrand, S-A, Verstraete, AG, Hels, T, Bernhoft, IM, Simonsen, KW, Lillsunde, P, Favretto, D, Ferrara, SD, Caplinskiene, M, Movig, KLL & Brookhuis, KA 2013, 'Random and systematic errors in case–control studies calculating the injury risk of driving under the influence of psychoactive substances' Accident Analysis & Prevention, vol 52, pp. 144-153., 10.1016/j.aap.2012.12.034

APA

CBE

Houwing S, Hagenzieker M, Mathijssen RPM, Legrand S-A, Verstraete AG, Hels T, Bernhoft IM, Simonsen KW, Lillsunde P, Favretto D, Ferrara SD, Caplinskiene M, Movig KLL, Brookhuis KA. 2013. Random and systematic errors in case–control studies calculating the injury risk of driving under the influence of psychoactive substances. Accident Analysis & Prevention. 52:144-153. Available from: 10.1016/j.aap.2012.12.034

MLA

Vancouver

Author

Houwing, Sjoerd; Hagenzieker, Marjan; Mathijssen, René P.M.; Legrand, Sara-Ann; Verstraete, Alain G.; Hels, Tove; Bernhoft, Inger Marie; Simonsen, Kirsten Wiese; Lillsunde, Pirjo; Favretto, Donata; Ferrara, Santo D.; Caplinskiene, Marija; Movig, Kris L.L.; Brookhuis, Karel A. / Random and systematic errors in case–control studies calculating the injury risk of driving under the influence of psychoactive substances.

In: Accident Analysis & Prevention, Vol. 52, 2013, p. 144-153.

Publication: Research - peer-reviewJournal article – Annual report year: 2012

Bibtex

@article{c485a57fabaa4a40acf8bdaf40981d9e,
title = "Random and systematic errors in case–control studies calculating the injury risk of driving under the influence of psychoactive substances",
keywords = "Accidents, Alcohols, Errors, Systematic errors",
publisher = "Elsevier Ltd.",
author = "Sjoerd Houwing and Marjan Hagenzieker and Mathijssen, {René P.M.} and Sara-Ann Legrand and Verstraete, {Alain G.} and Tove Hels and Bernhoft, {Inger Marie} and Simonsen, {Kirsten Wiese} and Pirjo Lillsunde and Donata Favretto and Ferrara, {Santo D.} and Marija Caplinskiene and Movig, {Kris L.L.} and Brookhuis, {Karel A.}",
year = "2013",
doi = "10.1016/j.aap.2012.12.034",
volume = "52",
pages = "144--153",
journal = "Accident Analysis & Prevention",
issn = "0001-4575",

}

RIS

TY - JOUR

T1 - Random and systematic errors in case–control studies calculating the injury risk of driving under the influence of psychoactive substances

A1 - Houwing,Sjoerd

A1 - Hagenzieker,Marjan

A1 - Mathijssen,René P.M.

A1 - Legrand,Sara-Ann

A1 - Verstraete,Alain G.

A1 - Hels,Tove

A1 - Bernhoft,Inger Marie

A1 - Simonsen,Kirsten Wiese

A1 - Lillsunde,Pirjo

A1 - Favretto,Donata

A1 - Ferrara,Santo D.

A1 - Caplinskiene,Marija

A1 - Movig,Kris L.L.

A1 - Brookhuis,Karel A.

AU - Houwing,Sjoerd

AU - Hagenzieker,Marjan

AU - Mathijssen,René P.M.

AU - Legrand,Sara-Ann

AU - Verstraete,Alain G.

AU - Hels,Tove

AU - Bernhoft,Inger Marie

AU - Simonsen,Kirsten Wiese

AU - Lillsunde,Pirjo

AU - Favretto,Donata

AU - Ferrara,Santo D.

AU - Caplinskiene,Marija

AU - Movig,Kris L.L.

AU - Brookhuis,Karel A.

PB - Elsevier Ltd.

PY - 2013

Y1 - 2013

N2 - Between 2006 and 2010, six population based case-control studies were conducted as part of the European research-project DRUID (DRiving Under the Influence of Drugs, alcohol and medicines). The aim of these case-control studies was to calculate odds ratios indicating the relative risk of serious injury in car crashes. The calculated odds ratios in these studies showed large variations, despite the use of uniform guidelines for the study designs. The main objective of the present article is to provide insight into the presence of random and systematic errors in the six DRUID case-control studies. Relevant information was gathered from the DRUID-reports for eleven indicators for errors. The results showed that differences between the odds ratios in the DRUID case-control studies may indeed be (partially) explained by random and systematic errors. Selection bias and errors due to small sample sizes and cell counts were the most frequently observed errors in the six DRUID case-control studies. Therefore, it is recommended that epidemiological studies that assess the risk of psychoactive substances in traffic pay specific attention to avoid these potential sources of random and systematic errors. The list of indicators that was identified in this study is useful both as guidance for systematic reviews and meta-analyses and for future epidemiological studies in the field of driving under the influence to minimize sources of errors already at the start of the study. © 2013 Published by Elsevier Ltd.

AB - Between 2006 and 2010, six population based case-control studies were conducted as part of the European research-project DRUID (DRiving Under the Influence of Drugs, alcohol and medicines). The aim of these case-control studies was to calculate odds ratios indicating the relative risk of serious injury in car crashes. The calculated odds ratios in these studies showed large variations, despite the use of uniform guidelines for the study designs. The main objective of the present article is to provide insight into the presence of random and systematic errors in the six DRUID case-control studies. Relevant information was gathered from the DRUID-reports for eleven indicators for errors. The results showed that differences between the odds ratios in the DRUID case-control studies may indeed be (partially) explained by random and systematic errors. Selection bias and errors due to small sample sizes and cell counts were the most frequently observed errors in the six DRUID case-control studies. Therefore, it is recommended that epidemiological studies that assess the risk of psychoactive substances in traffic pay specific attention to avoid these potential sources of random and systematic errors. The list of indicators that was identified in this study is useful both as guidance for systematic reviews and meta-analyses and for future epidemiological studies in the field of driving under the influence to minimize sources of errors already at the start of the study. © 2013 Published by Elsevier Ltd.

KW - Accidents

KW - Alcohols

KW - Errors

KW - Systematic errors

U2 - 10.1016/j.aap.2012.12.034

DO - 10.1016/j.aap.2012.12.034

JO - Accident Analysis & Prevention

JF - Accident Analysis & Prevention

SN - 0001-4575

VL - 52

SP - 144

EP - 153

ER -