Effect of kinetic parameters on heterologous protein production: a sysbio approach

Publication: Research - peer-reviewPoster – Annual report year: 2011

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To improve the expression and secretion of heterologous proteins in the filamentous grampositive bacteria, Streptomyces lividans, bioprocessing strategies were developed. A mathematical model was constructed to study the effects of the process kinetic parameters on the production of the model-protein RFP. The model describes the dynamics of glucose consumption and formation of biomass in addition to RFP production. The model was also extended to describe a two substrate condition.
Original languageEnglish
Publication date2011
StatePublished

Conference

Conference6th Danish Conference on Biotechnology and Molecular Biology
Number6
CountryDenmark
CityVejle
Period26/05/1127/05/11
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