Dynamical patterns of calcium signaling in a functional model of neuron-astrocyte networks

Publication: Research - peer-reviewJournal article – Annual report year: 2009

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We propose a functional mathematical model for neuron-astrocyte networks. The model incorporates elements of the tripartite synapse and the spatial branching structure of coupled astrocytes. We consider glutamate-induced calcium signaling as a specific mode of excitability and transmission in astrocytic-neuronal networks. We reproduce local and global dynamical patterns observed experimentally.
Original languageEnglish
JournalJournal of Biological Physics
Publication date2009
Volume35
Issue4
Pages425-445
ISSN0092-0606
DOIs
StatePublished
CitationsWeb of Science® Times Cited: 25

Keywords

  • Astrocyte, Tripartite synapse, Modeling, Neuron, Calcium waves
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