TY - JOUR

T1 - Distribution of vitamins A (retinol) and E (alpha-tocopherol) in polar bear kidney: Implications for biomarker studies

A1 - Bechshøft,T.Ø.

A1 - Jakobsen,Jette

A1 - Sonne,C.

A1 - Dietz,R.

AU - Bechshøft,T.Ø.

AU - Jakobsen,Jette

AU - Sonne,C.

AU - Dietz,R.

PB - Elsevier BV

PY - 2011

Y1 - 2011

N2 - Vitamins A and E content of inner organs, among these the kidneys, are increasingly being used as an indicator of adverse effects caused to the organism by e.g. environmental contaminants. In general, only a renal sub sample is used for analyses, and it is thus essential to know which part of the organ to sample in order to get a representative value for this important biomarker. The aim here was to assess the distribution of vitamins A (retinol) and E (α-tocopherol) within the polar bear multireniculate kidney (i.e. polar vs. medial position) and also within the cortex vs. medulla of each separate renculi. The results showed no significant difference between the medial and polar renculi with regards to either retinol (p=0.44) or α-tocopherol (p=0.75). There were, however, significant differences between cortex and medulla for both vitamins (retinol, p=0.0003; α-tocopherol, p

AB - Vitamins A and E content of inner organs, among these the kidneys, are increasingly being used as an indicator of adverse effects caused to the organism by e.g. environmental contaminants. In general, only a renal sub sample is used for analyses, and it is thus essential to know which part of the organ to sample in order to get a representative value for this important biomarker. The aim here was to assess the distribution of vitamins A (retinol) and E (α-tocopherol) within the polar bear multireniculate kidney (i.e. polar vs. medial position) and also within the cortex vs. medulla of each separate renculi. The results showed no significant difference between the medial and polar renculi with regards to either retinol (p=0.44) or α-tocopherol (p=0.75). There were, however, significant differences between cortex and medulla for both vitamins (retinol, p=0.0003; α-tocopherol, p

KW - Retinol

KW - Vitamin

KW - Renculi

KW - Kidney

KW - Ursus maritimus

KW - Tocopherol

U2 - 10.1016/j.scitotenv.2011.05.036

DO - 10.1016/j.scitotenv.2011.05.036

JO - Science of the Total Environment

JF - Science of the Total Environment

SN - 0048-9697

IS - 18

VL - 409

SP - 3508

EP - 3511

ER -