Differentiation between serological responses to Brucella suis and Yersinia enterocolitica serotype O : 9 after natural or experimental infection in pigs

Publication: Research - peer-review › Journal article – Annual report year: 2006

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Differentiation between serological responses to Brucella suis and Yersinia enterocolitica serotype O : 9 after natural or experimental infection in pigs. / Jungersen, Gregers ; Sørensen, Vibeke ; Giese, Steen Bjørck; Stack, J. A.; Riber, Ulla.

In: Epidemiology and Infection, Vol. 134, No. 2, 2006, p. 347-357.

Publication: Research - peer-review › Journal article – Annual report year: 2006

In: Epidemiology and Infection, Vol. 134, No. 2, 2006, p. 347-357.

Publication: Research - peer-review › Journal article – Annual report year: 2006

Bibtex

@article{883e5f01319046bd954dd482debd153f,

title = "Differentiation between serological responses to Brucella suis and Yersinia enterocolitica serotype O : 9 after natural or experimental infection in pigs",

publisher = "Cambridge University Press",

author = "Gregers Jungersen and Vibeke Sørensen and Giese, {Steen Bjørck} and Stack, {J. A.} and Ulla Riber",

year = "2006",

volume = "134",

number = "2",

pages = "347--357",

journal = "Epidemiology and Infection",

issn = "0950-2688",

}

RIS

TY - JOUR

T1 - Differentiation between serological responses to Brucella suis and Yersinia enterocolitica serotype O : 9 after natural or experimental infection in pigs

A1 - Jungersen,Gregers

A1 - Sørensen,Vibeke

A1 - Giese,Steen Bjørck

A1 - Stack,J. A.

A1 - Riber,Ulla

AU - Jungersen,Gregers

AU - Sørensen,Vibeke

AU - Giese,Steen Bjørck

AU - Stack,J. A.

AU - Riber,Ulla

PB - Cambridge University Press

PY - 2006

Y1 - 2006

N2 - False-positive serological reactions (FPSR) due to infections with Yersinia enterocolitica serotype 0: 9 (YeO:9) are a problem in tests for brucellosis. In the present study, FPSR in classical and novel tests for brucellosis following experimental infections of pigs with YeO:9 were compared with responses of B. suis biovar 2-inoculated pigs. FPSR were limited to 2-9 weeks post-YeO:9 inoculation, while B. suis-infected pigs were test-positive throughout the 21-week period of investigation. Although YeO:9-inoculated pigs exhibited FPSR in Brucella tests for a limited period of time, the serological responses in a YeO:9-purified O-antigen indirect ELISA did not decrease accordingly. Analysis of available cross-sectional serum samples from pig herds naturally infected with YeO: 9 or B. suis biovar 2 confirmed that the observed difference in the duration of the serological responses between the two infections could be used to discriminate between herds infected with B. suis biovar 2 and YeO:9.

AB - False-positive serological reactions (FPSR) due to infections with Yersinia enterocolitica serotype 0: 9 (YeO:9) are a problem in tests for brucellosis. In the present study, FPSR in classical and novel tests for brucellosis following experimental infections of pigs with YeO:9 were compared with responses of B. suis biovar 2-inoculated pigs. FPSR were limited to 2-9 weeks post-YeO:9 inoculation, while B. suis-infected pigs were test-positive throughout the 21-week period of investigation. Although YeO:9-inoculated pigs exhibited FPSR in Brucella tests for a limited period of time, the serological responses in a YeO:9-purified O-antigen indirect ELISA did not decrease accordingly. Analysis of available cross-sectional serum samples from pig herds naturally infected with YeO: 9 or B. suis biovar 2 confirmed that the observed difference in the duration of the serological responses between the two infections could be used to discriminate between herds infected with B. suis biovar 2 and YeO:9.

JO - Epidemiology and Infection

JF - Epidemiology and Infection

SN - 0950-2688

IS - 2

VL - 134

SP - 347

EP - 357

ER -