TY - JOUR

T1 - Determinants of vitamin D status in a general population of Danish adults

A1 - Thuesen,B.

A1 - Husemoen,L.

A1 - Fenger,M.

A1 - Jakobsen,Jette

A1 - Schwarz,P.

A1 - Toft,U.

A1 - Ovesen,L.

A1 - Jørgensen,T.

A1 - Linneberg,A.

AU - Thuesen,B.

AU - Husemoen,L.

AU - Fenger,M.

AU - Jakobsen,Jette

AU - Schwarz,P.

AU - Toft,U.

AU - Ovesen,L.

AU - Jørgensen,T.

AU - Linneberg,A.

PB - Elsevier Inc.

PY - 2012

Y1 - 2012

N2 - Background and aimsDanish legislation regarding food fortification has been very restrictive and vitamin D deficiency is thought to be common in Denmark due to inadequate dietary intakes and the fact that in Denmark (latitude 56°N) vitamin D is only synthesized in the skin after exposure to solar radiation during summertime (April–September). The purpose of this study was to evaluate the vitamin D status of a general adult population in Denmark and, in addition, associations between vitamin D status and distinct lifestyle factors were studied. MethodsA random sample of 6784 persons from a general population aged 30–60years participated in a health examination in 1999–2001. Serum samples from all participants were stored and levels of 25-hydroxyvitamin D (25(OH)D) were measured by HPLC in 2009. The method was compared to another HPLC method. Information on dietary intake of vitamin D and other lifestyle factors were obtained by questionnaires. A total of 6146 persons defined as ethnic Danes and with successful measurements of 25(OH)D were included in the analyses. ResultsThe overall prevalence of vitamin D deficiency (25(OH)D

AB - Background and aimsDanish legislation regarding food fortification has been very restrictive and vitamin D deficiency is thought to be common in Denmark due to inadequate dietary intakes and the fact that in Denmark (latitude 56°N) vitamin D is only synthesized in the skin after exposure to solar radiation during summertime (April–September). The purpose of this study was to evaluate the vitamin D status of a general adult population in Denmark and, in addition, associations between vitamin D status and distinct lifestyle factors were studied. MethodsA random sample of 6784 persons from a general population aged 30–60years participated in a health examination in 1999–2001. Serum samples from all participants were stored and levels of 25-hydroxyvitamin D (25(OH)D) were measured by HPLC in 2009. The method was compared to another HPLC method. Information on dietary intake of vitamin D and other lifestyle factors were obtained by questionnaires. A total of 6146 persons defined as ethnic Danes and with successful measurements of 25(OH)D were included in the analyses. ResultsThe overall prevalence of vitamin D deficiency (25(OH)D

U2 - 10.1016/j.bone.2011.12.016

DO - 10.1016/j.bone.2011.12.016

JO - Bone

JF - Bone

SN - 8756-3282

IS - 3

VL - 50

SP - 605

EP - 610

ER -