Standard

Co-circulation of two extremely divergent serotype SAT 2 lineages in Kenya highlights challenges to foot-and-mouth disease control.. / Sangula, Abraham; Belsham, Graham; Muwanika, Vincent; Heller, Rasmus; Balinda, Sheila; Siegismund, Hans.

In: Archives of Virology, Vol. 155, 2010, p. 1625-1630.

Publication: Research - peer-reviewJournal article – Annual report year: 2010

Harvard

APA

CBE

MLA

Vancouver

Author

Sangula, Abraham; Belsham, Graham; Muwanika, Vincent; Heller, Rasmus; Balinda, Sheila; Siegismund, Hans / Co-circulation of two extremely divergent serotype SAT 2 lineages in Kenya highlights challenges to foot-and-mouth disease control..

In: Archives of Virology, Vol. 155, 2010, p. 1625-1630.

Publication: Research - peer-reviewJournal article – Annual report year: 2010

Bibtex

@article{2be7e989ff22456c8c1da0939861d158,
title = "Co-circulation of two extremely divergent serotype SAT 2 lineages in Kenya highlights challenges to foot-and-mouth disease control.",
publisher = "Springer Wien",
author = "Abraham Sangula and Graham Belsham and Vincent Muwanika and Rasmus Heller and Sheila Balinda and Hans Siegismund",
year = "2010",
doi = "10.1007/s00705-010-0742-9",
volume = "155",
pages = "1625--1630",
journal = "Archives of Virology",
issn = "0304-8608",

}

RIS

TY - JOUR

T1 - Co-circulation of two extremely divergent serotype SAT 2 lineages in Kenya highlights challenges to foot-and-mouth disease control.

A1 - Sangula,Abraham

A1 - Belsham,Graham

A1 - Muwanika,Vincent

A1 - Heller,Rasmus

A1 - Balinda,Sheila

A1 - Siegismund,Hans

AU - Sangula,Abraham

AU - Belsham,Graham

AU - Muwanika,Vincent

AU - Heller,Rasmus

AU - Balinda,Sheila

AU - Siegismund,Hans

PB - Springer Wien

PY - 2010

Y1 - 2010

N2 - Amongst the SAT serotypes of foot-and-mouth disease virus (FMDV), the SAT 2 serotype is the most widely distributed throughout sub-Saharan Africa. Kenyan serotype SAT 2 viruses have been reported to display the highest genetic diversity for the serotype globally. This complicates diagnosis and control, and it is essential that patterns of virus circulation are known in order to overcome these difficulties. This study was undertaken to establish patterns of evolution of FMDV serotype SAT 2 in Kenya using complete VP1 coding sequences in a dataset of 65 sequences from Africa, collected over a period of 50 years. Two highly divergent lineages were observed to co-circulate, and occasional trans-boundary spread was inferred, emphasizing the value of constant monitoring and characterization of field strains for improved diagnosis and appropriate vaccine application as well as the need for regional approaches to control.

AB - Amongst the SAT serotypes of foot-and-mouth disease virus (FMDV), the SAT 2 serotype is the most widely distributed throughout sub-Saharan Africa. Kenyan serotype SAT 2 viruses have been reported to display the highest genetic diversity for the serotype globally. This complicates diagnosis and control, and it is essential that patterns of virus circulation are known in order to overcome these difficulties. This study was undertaken to establish patterns of evolution of FMDV serotype SAT 2 in Kenya using complete VP1 coding sequences in a dataset of 65 sequences from Africa, collected over a period of 50 years. Two highly divergent lineages were observed to co-circulate, and occasional trans-boundary spread was inferred, emphasizing the value of constant monitoring and characterization of field strains for improved diagnosis and appropriate vaccine application as well as the need for regional approaches to control.

U2 - 10.1007/s00705-010-0742-9

DO - 10.1007/s00705-010-0742-9

JO - Archives of Virology

JF - Archives of Virology

SN - 0304-8608

VL - 155

SP - 1625

EP - 1630

ER -