View graph of relations

A highly efficient method for functionalizing nanoparticles and directly quantifying conjugation efficiency and ligand surface density has been developed. Attachment of 3-azido-modifed RGD-peptides to PEGylated liposomes was achieved by using Cu-free click conditions. Upon coupling a fluorophore is formed, which could be utilized to monitor conjugation efficiency and the obtained ligand surface density in situ, without prior purification.
Original languageEnglish
JournalChemistry - A European journal
Publication date2011
Volume17
Issue12
Pages3326-3331
ISSN0947-6539
DOIs
StatePublished
CitationsWeb of Science® Times Cited: 5

Keywords

  • Coumarin, Surface functionalization, Nanoparticles, Lposomes, Click chemistry
Download as:
Download as PDF
Select render style:
APAAuthorCBEHarvardMLAStandardVancouverShortLong
PDF
Download as HTML
Select render style:
APAAuthorCBEHarvardMLAStandardVancouverShortLong
HTML
Download as Word
Select render style:
APAAuthorCBEHarvardMLAStandardVancouverShortLong
Word

ID: 5618113