Brachyspira murdochii colitis in pigs

Publication: Research - peer-reviewJournal article – Annual report year: 2010

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The weakly beta-hemolytic porcine spirochete Brachyspira murdochii is considered a normal intestinal commensal. In the present study, however, a field case of B murdochii–associated catarrhal colitis was identified in a pig, as characterized by extensive spirochetal colonization of the surface epithelium. Experimentally, 8 weaned pigs were challenged with the B murdochii isolate, reproducing catarrhal colitis in 2 animals. By applying fluorescent in situ hybridization using a species-specific oligonucleotide probe targeting 23S rRNA, B murdochii organisms were found in high numbers and were closely associated with the surface epithelium in the pigs with catarrhal colitis. The results indicate that, when present in high numbers, B murdochii is low pathogenic for pigs.
Original languageEnglish
JournalVeterinary Pathology
Publication date2010
Volume47
Issue2
Pages334-338
ISSN0300-9858
DOIs
StatePublished
CitationsWeb of Science® Times Cited: 12
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