TY - CONF

T1 - Bio Optofluidics Cell Sorter – cell-BOCS Concept and Applications

A1 - Roth,Tue

A1 - Glückstad,Jesper

AU - Roth,Tue

AU - Glückstad,Jesper

PB - S P I E - International Society for Optical Engineering

PY - 2012

Y1 - 2012

N2 - The cell-BOCS is a novel microfluidics based cell-sorting instrument utilizing next generation optical trapping technology developed at the Technical University of Denmark. It is targeted emerging bio-medical research and diagnostics markets where it for certain applications offers a number of advantages over conventional fluorescence activated cell-sorting (FACS™) technology. Advantages include gentle handling of cells, sterile sorting, easy operation, small footprint and lower cost allowing out-of-core-facility use. Application examples are found within sorting of fragile transfected cells, high value samples and primary cell lines, where traditional FACS technology has limited application due to it’s droplet-based approach to cell-sorting. In the diagnostics field, in particular applying the cell-BOCS for isolating pure populations of circulating tumor cells is an area that has generated a lot of interest.

AB - The cell-BOCS is a novel microfluidics based cell-sorting instrument utilizing next generation optical trapping technology developed at the Technical University of Denmark. It is targeted emerging bio-medical research and diagnostics markets where it for certain applications offers a number of advantages over conventional fluorescence activated cell-sorting (FACS™) technology. Advantages include gentle handling of cells, sterile sorting, easy operation, small footprint and lower cost allowing out-of-core-facility use. Application examples are found within sorting of fragile transfected cells, high value samples and primary cell lines, where traditional FACS technology has limited application due to it’s droplet-based approach to cell-sorting. In the diagnostics field, in particular applying the cell-BOCS for isolating pure populations of circulating tumor cells is an area that has generated a lot of interest.

KW - Flow cytometry

KW - Microfluidics

KW - Optical tweezers

KW - Fluorescence activated cell sorting

KW - Optical trapping

UR - http://spie.org/x2584.xml

UR - http://optorobotix.com/

U2 - 10.1117/12.909783

DO - 10.1117/12.909783

JO - Proceedings of SPIE, the International Society for Optical Engineering

JF - Proceedings of SPIE, the International Society for Optical Engineering

SN - 1605-7422

VL - 8274

SP - 82740J

ER -