Bio Optofluidics Cell Sorter – cell-BOCS Concept and Applications

Publication: Research - peer-reviewConference article – Annual report year: 2012

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The cell-BOCS is a novel microfluidics based cell-sorting instrument utilizing next generation optical trapping technology developed at the Technical University of Denmark. It is targeted emerging bio-medical research and diagnostics markets where it for certain applications offers a number of advantages over conventional fluorescence activated cell-sorting (FACS™) technology. Advantages include gentle handling of cells, sterile sorting, easy operation, small footprint and lower cost allowing out-of-core-facility use. Application examples are found within sorting of fragile transfected cells, high value samples and primary cell lines, where traditional FACS technology has limited application due to it’s droplet-based approach to cell-sorting. In the diagnostics field, in particular applying the cell-BOCS for isolating pure populations of circulating tumor cells is an area that has generated a lot of interest.
Original languageEnglish
JournalProceedings of SPIE, the International Society for Optical Engineering
Publication date2012
Volume8274
Pages82740J
ISSN0277-786X
DOIs
StatePublished

Conference

ConferenceSPIE Photonics West
CountryUnited States
CitySan Francisco, California
Period21/01/1226/01/12
CitationsWeb of Science® Times Cited: 0

Keywords

  • Flow cytometry, Microfluidics, Optical tweezers, Fluorescence activated cell sorting, Optical trapping
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