A systematic synthesis and design methodology to achieve process intensification in (bio) chemical processes

Publication: Research - peer-reviewArticle in proceedings – Annual report year: 2010

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Process intensification (PI) has the potential to improve existing processes or create new process options which are needed in order to produce products using more sustainable methods. PI creates an enormous number of process options. In order to manage the complexity of options in which a feasible and optimal process solution may exist, the application of process synthesis tools results in the development of a systematic methodology to implement PI. Starting from an analysis of existing processes, this methodology generates a set of feasible process options and reduces their number through a number of screening steps until from the remaining feasible options, the optimal is found. The application of this systematic methodology through a computer-aided framework is presented through a case study, the chemo-enzymatic synthesis of N-acetyl-D-neuraminic acid (Neu5Ac).
Original languageEnglish
TitleProceedings of the 20th European Symposium on Computer Aided Process Engineering
PublisherElsevier Science
Publication date2010
Pages241-246
ISBN (print)04-44-53569-1, 978-0-444-53569-6
DOIs
StatePublished

Conference

Conference20th European Symposium on Computer Aided Process Engineering
Number20
CountryItaly
CityIschia
Period06/06/1009/06/10
Internet addresshttp://www.aidic.it/escape20/
NameComputer - Aided Chemical Engineering
Volume28
ISSN (Print)1570-7946
CitationsWeb of Science® Times Cited: No match on DOI

Keywords

  • Methodology, Process synthesis, Process intensification, Biocatalysis, N-acetylneuraminic acid (Neu5Ac)
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