A Generic Framework for Systematic Design of Process Monitoring and Control System for Crystallization Processes
Publication: Research › Conference abstract for conference – Annual report year: 2012
The objectives of this work are to develop a generic systematic design framework for monitoring and control systems applicable to a wide range of crystallization processes and operational scenarios. This framework contains a generic multi-dimensional modelling framework and features for design of operational scenarios and for design of PAT systems. The generality of this approach allows the users to generate a wide range of problem-system specific models through the generic multi-dimensional modelling framework . In order to obtain the desired crystal products, an analytical CSD estimator and a response surface method are employed to generate the operational policy needed to match the desired target CSD. The generated operational policies provide the supersaturation set point and by maintaining the operation at this point, the targeted CSD is achieved. The resulting problem-system specific models and the operational policies become ready for use in model-based design and control/analysis of crystallization operations within a model-based process monitoring and control system (PAT system) . The application of the systematic design framework will be highlighted through a potassium dihydrogen phosphate (KDP) crystallization process case study where the objective is to obtain a desired two-dimensional CSD and crystal shape. Also, integrated visualization tools are used together with the generated data for process control and for product (crystal) property monitoring, illustrating, thereby, the power and unique features of this systematic model-based design procedure.
|Conference||22nd European Symposium on Computer Aided Process Engineering|
|Period||17-06-12 → 22-06-12|
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- Process monitoring and control, Analytical estimator, Crystal distribution, Crystal shape