The main hypothesis behind this project is that not only the number of pathogenic bacteria in a given food product, but also their physiological condition, is decisive for whether or not the contaminated food will cause disease after ingestion. The influence of a number of food-related environmental conditions on the infectivity of Listeria in vitro and in vivo is investigated. The observations of infectivity are coupled to the expression patterns of Listeria monocytogenes as monitored by use of micro arrays. The obtained results will be highly relevant for risk assessment of Listeria in various types of food.
|Period||01/03/2003 → 31/12/2006|