The aim of FUN OCT is to expand the non-invasive optical biopsy capability of optical coherence tomography (OCT) and combine it with multiphoton tomography (MT) to develop novel functional capabilities enabling 'morphofunctional' performance, i.e. the fusion of anatomic and functional imaging at the cellular resolution level. These methodologies will enable unprecedented non-invasive detection of depth-resolved physiological, metabolic and molecular specific tissue information.