The Center for Biological Sequence Analysis conducts basic research in bioinformatics - a rapidly growing area in the field of molecular biology. The overall goal of the research is to obtain knowledge of the complex relations between sequence composition - the content and order of the chemical building blocks - and macromolecular structure and function. In addition, the research is aimed at creating entirely new possibilities in the study of evolutionary processes by comparison of sequence patterns across species. The tremendous growth in the amount of sequence and structure data has brought about a radical change in the possibilities of developing powerful computer methods for classification, prediction and comparison of molecular structure and function. The work of the center is especially focussed on novel data driven computational methods, such as artificial neural networks and hidden Markov models. Please see http://www.cbs.dtu.dk/ for further information.