Zoltan Imre Szallasi

  1. 2016
  2. Published

    A robust prognostic gene expression signature for early stage lung adenocarcinoma. / Krzystanek, Marcin; Moldvay, Judit; Szüts, David; Szallasi, Zoltan Imre; Eklund, Aron Charles.

    In: Biomarker Research, Vol. 4, No. 4, 2016.

    Publication: Research - peer-reviewJournal article – Annual report year: 2016

  3. Published

    MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy. / Neupane, Manish; Clark, Allison P.; Landini, Serena; Birkbak, Nicolai Juul; Eklund, Aron Charles; Lim, Elgene; Culhane, Aedin C.; Barry, William T.; Schumacher, Steven E.; Beroukhim, Rameen; Szallasi, Zoltan Imre; Vidal, Marc; Hill, David E.; Silver, Daniel P.

    In: Cancer Discovery, Vol. 6, No. 1, 2016, p. 45-58.

    Publication: Research - peer-reviewJournal article – Annual report year: 2016

  4. 2015
  5. Published

    A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men. / Petrovics, Gyorgy; Li, Hua; Stümpel, Tanja; Tan, Shyh-Han; Young, Denise; Katta, Shilpa; Li, Qiyuan; Ying, Kai; Klocke, Bernward; Ravindranath, Lakshmi; Kohaar, Indu; Chen, Yongmei; Ribli, Dezső; Grote, Korbinian; Zou, Hua; Cheng, Joseph; Dalgard, Clifton L.; Zhang, Shimin; Csabai, Istvan; Kagan, Jacob; Takeda, David; Loda, Massimo; Scherf, Matthias; Seifert, Martin; Gaiser, Timo; McLeod, David G.; Szallasi, Zoltan Imre; Ebner, Reinhard; Werner, Thomas; Sesterhenn, Isabell A; Freedman, Matthew; Dobi, Albert; Srivastava, Shiv.

    In: EBioMedicine, Vol. 2, No. 12, 2015, p. 1957-1964.

    Publication: Research - peer-reviewJournal article – Annual report year: 2016

  6. Published

    CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants.. / Spisák, Sándor; Lawrenson, Kate; Fu, Yanfang; Csabai, Istvan; Cottman, Rebecca T.; Seo, Ji-Heui; Haiman, Christopher; Han, Ying; Lenci, Romina; Li, Qiyuan; Tisza, Viktória; Szallasi, Zoltan Imre; Herbert, Zachery T.; Chabot, Matthew; Pomerantz, Mark; Solymosi, Norbert; Gayther, Simon A.; Joung, J. Keith; Freedman, Matthew L.

    In: Nature Medicine, Vol. 21, No. 11, 2015, p. 1357-1363.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  7. Published

    Clonal status of actionable driver events and the timing of mutational processes in cancer evolution. / McGranahan, Nicholas; Favero, Francesco; de Bruin, Elza C.; Birkbak, Nicolai Juul; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Science Translational Medicine, Vol. 7, No. 283, 283ra54, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  8. Published
  9. Published

    Relationship of postoperative thrombocytosis and survival of patients with colorectal cancer. / Josa, Valeria; Krzystanek, Marcin; Eklund, Aron Charles; Salamon, Ferenc; Zarand, Attila; Szallasi, Zoltan Imre; Baranyai, Zsolt.

    In: International Journal of Surgery, Vol. 18, 2015, p. 1-6.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  10. Published
  11. Published

    SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. / Kanu, N.; Grönroos, E.; Martinez, P.; Burrell, R. A.; Yi Goh, X.; Bartkova, J.; Maya-Mendoza, A.; Mistrík, M.; Rowan, A. J.; Patel, H.; Rabinowitz, A.; East, P.; Wilson, G.; Santos, C. R.; McGranahan, N.; Gulati, S.; Gerlinger, M.; Birkbak, Nicolai Juul; Joshi, Tejal; Alexandrov, L. B.; Stratton, M. R.; Powles, T.; Matthews, N.; Bates, P. A.; Stewart, A.; Szallasi, Zoltan Imre; Larkin, J.; Bartek, J.; Swanton, C.

    In: Oncogene, Vol. 34, 2015, p. 5699-5708.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  12. Published

    Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer. / Su, Ying; Subedee, Ashim; Bloushtain-Qimron, Noga; Savova, Virginia; Krzystanek, Marcin; Li, Lewyn; Marusyk, Andriy; Tabassum, Doris P.; Zak, Alexander; Szallasi, Zoltan Imre.

    In: Cell Reports, Vol. 11, No. 10, 2015, p. 1549-1563.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  13. Published

    Thrombocytosis of Liver Metastasis from Colorectal Cancer as Predictive Factor. / Josa, Valeria; Krzystanek, Marcin; Vass, Tamas; Lang, Tamas; Juhasz, Viktoria; Szilagyi, Kamilla; Tihanyi, Balazs; Harsanyi, Laszlo; Szallasi, Zoltan Imre; Salamon, Ferenc; Baranyai, Zsolt.

    In: Pathology and Oncology Research, Vol. 21, No. 4, 2015, p. 991-997.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  14. Published

    TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen. / Marquard, Andrea Marion; Birkbak, Nicolai Juul; Thomas, Cecilia Engel; Favero, Francesco; Krzystanek, Marcin; Lefebvre, Celine; Ferté, Charles; Jamal-Hanjani, Mariam; Wilson, Gareth A.; Shafi, Seema; Swanton, Charles; André, Fabrice; Szallasi, Zoltan Imre; Eklund, Aron Charles.

    In: BMC Medical Genomics, Vol. 8, No. 58, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  15. 2014
  16. Published

    A pan-cancer analysis of inferred homologous recombination deficiency identifies potential platinum benefit in novel subtypes. / Marquard, Andrea Marion; Eklund, Aron Charles; Wang, Zhigang C.; Richardson, Andrea L.; Szallasi, Zoltan Imre; Birkbak, Nicolai Juul.

    In: Cancer Research, Vol. 74, No. 19 - Supplement, 2822, 2014.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2015

  17. Published

    Computational and Experimental Approaches to Cancer Biomarker Discovery. / Krzystanek, Marcin; Szallasi, Zoltan Imre (Main supervisor); Eklund, Aron Charles (Supervisor).

    Kgs. Lyngby : Technical University of Denmark, 2014. 96 p.

    Publication: ResearchPh.D. thesis – Annual report year: 2015

  18. Published

    Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma. / Kelderman, Sander; Heemskerk, Bianca; van Tinteren, Harm; van den Brom, Rob R. H.; A. P. Hospers, Geke; van den Eertwegh, Alfonsus J. M.; W. Kapiteijn, Ellen; Willem B. de Groot, Jan; Soetekouw, Patricia; L. Jansen, Rob; Fiets , Edward; J. S. Furness, Andrew; Renn, Alexandra; Krzystanek, Marcin; Szallasi, Zoltan Imre; Lorigan, Paul; Gore, Martin E.; N. M. Schumacher, Ton; B. A. G. Haanen, John; Larkin, James M.G.; U. Blank, Christian.

    In: Cancer Immunology, Immunotherapy, Vol. 63, No. 5, 2014, p. 449-458.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  19. Published

    Systematic Evaluation of the Prognostic Impact and Intratumour Heterogeneity of Clear Cell Renal Cell Carcinoma Biomarkers. / Gulati, Sakshi; Martinez, Pierre; Joshi, Tejal; Birkbak, Nicolai Juul; Santos, Claudio R.; Rowan, Andrew J.; Pickering, Lisa; Gore, Martin; Larkin, James; Szallasi, Zoltan Imre; Bates, Paul A.; Swanton, Charles; Gerlinger, Marco.

    In: European Urology, Vol. 66, No. 5, 2014, p. 936-948.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  20. Published

    The comparison of thrombocytosis and platelet-lymphocyte ratio as potential prognostic markers in colorectal cancer. / Baranyai, Zsolt; Krzystanek, Marcin; Josa, Valeria; Dede, Kristof; Ágoston, E.; Szasz, A. Marcell; Sinko, Daniel; Szarvas, Viktor; Salamon, Ferenc; Eklund, Aron Charles; Szallasi, Zoltan Imre; Jakab, Ferenc.

    In: Thrombosis and Haemostasis, Vol. 111, No. 3, 2014, p. 483-490.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  21. Published

    The Genome of the Chicken DT40 Bursal Lymphoma Cell Line. / Molnar, Janos; Poti, Adam; Pipek, Orsolya; Krzystanek, Marcin; Kanu, Nnennaya; Swanton, Charles; Tusnady, Gabor E.; Szallasi, Zoltan Imre; Csabai, Istvan; Szuets, David.

    In: G3: Genes, Genomes, Genetics (Bethesda), Vol. 4, No. 11, 2014, p. 2231-2240.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  22. Published

    Thrombocytosis portends adverse prognostic significance in patients with stage II colorectal carcinoma. / Guo, Tianhua; Krzystanek, Marcin; Szallasi, Zoltan Imre; Szallasi, Arpad.

    In: F1000Research, Vol. 3, No. 180, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  23. Published

    Tolerance of Whole-Genome Doubling Propagates Chromosomal Instability and Accelerates Cancer Genome Evolution. / Dewhurst, Sally M.; McGranahan, Nicholas; Burrell, Rebecca A.; Rowan, Andrew J.; Grönroos, Eva; Endesfelder, David; Joshi, Tejal; Mouradov, Dmitri; Gibbs, Peter; Ward, Robyn L.; Hawkins, Nicholas J.; Szallasi, Zoltan Imre; Sieber, Oliver M.; Swanton, Charles.

    In: Cancer Discovery, Vol. 4, No. 2, 2014, p. 175-185.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  24. 2013
  25. Published

    31P gain of chromosomal region 15q26 cause increased expression of blm and fanci, and is associated with sensitivity to platinum chemotherapy in triple negative breast cancer. / Birkbak, Nicolai Juul; Li, Y.; Bowman-Collin, C.; Iglehart, J.D.; Silver, D.; Wang, Z.C.; Szallasi, Zoltan Imre; Richardson, A.

    In: Annals of Oncology, Vol. 24, No. suppl 3, 2013, p. iii22.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  26. Published
  27. Published

    Biasogram: visualization of confounding technical bias in gene expression data.. / Krzystanek, Marcin; Szallasi, Zoltan Imre; Eklund, Aron Charles.

    In: P L o S One, Vol. 8, No. 4, 2013, p. e61872.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  28. Published

    Deconvoluting complex tissues for expression quantitative trait locus-based analyses. / Seo, Ji-Heui; Li, Qiyuan; Fatima, Aquila; Eklund, Aron Charles; Szallasi, Zoltan Imre; Polyak, Kornelia; Richardson, Andrea L.; Freedman, Matthew L.

    In: Royal Society of London. Philosophical Transactions B. Biological Sciences, Vol. 368, No. 1620, 2013, p. 20120363-20120363.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  29. Published

    Methods for predicting anti-cancer response. / Szallasi, Zoltan Imre (Inventor); Eklund, Aron Charles (Inventor); Birkbak, Nicolai Juul (Inventor); Richardson, Andrea L. (Inventor); Silver, Daniel P. (Inventor); Wang, Zhigang (Inventor).

    IPC No.: C12Q1/68. Patent No.: WO2013130347. Sep 06, 2013.

    Publication: ResearchPatent – Annual report year: 2012

  30. Published

    Parallel evolution of tumor subclones mimics diversity between tumors. / Martinez, Pierre; Birkbak, Nicolai Juul; Gerlinger, Marco; McGranahan, Nicholas; Burrell, Rebecca; Rowan, Andrew; Joshi, Tejal; Fisher, Rosalie; Larkin, James; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Journal of Pathology, Vol. 230, No. 4, 2013, p. 356-364.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  31. Published

    Prognostic and Predictive Markers in Metastatic Renal Cell Carcinoma. / Khattak, Muhammad A.; Bakr, Farrah; Krzystanek, Marcin; Szallasi, Zoltan Imre; Gerlinger, Marco; Santos, Claudio; Swanton, Charles; Pickering, Lisa M.; Gore, Martin E.; Larkin, James M.G.

    In: Journal of Clinical Oncology, Vol. 31, No. 7, 2013, p. 20971-972.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  32. Published

    The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer.. / Szász, Attila Marcell; Li, Qiyuan; Eklund, Aron Charles; Sztupinszki, Zsófia; Rowan, Andrew; Tőkés, Anna-Mária; Székely, Borbála; Kiss, András; Szendrői, Miklós; Győrffy, Balázs; Szallasi, Zoltan Imre; Swanton, Charles; Kulka, Janina.

    In: PloS one., Vol. 8, No. 2, 2013, p. e56707.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  33. Published

    Tumor Mutation Burden Forecasts Outcome in Ovarian Cancer with BRCA1 or BRCA2 Mutations. / Birkbak, Nicolai Juul; Kochupurakkal, Bose; Gonzalez-Izarzugaza, Jose Maria; Eklund, Aron Charles; Li, Yang; Liu, Joyce; Szallasi, Zoltan Imre; Matulonis, Ursula A. ; Richardson, Andrea L. ; Iglehart, J. Dirk ; Wang, Zhigang C.

    In: P L o S One, Vol. 8, No. 11, e80023, 2013.

    Publication: Research - peer-reviewJournal article – Annual report year: 2013

  34. 2012
  35. Published

    CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid‐specific cancer cell death through autophagy induction. / Lee, Alvin J. X.; Roylance, Rebecca; Sander, Jil; Gorman, Patricia; Endesfelder, David; Kschischo, Maik; Jones, Neil P.; East, Philip; Nicke, Barbara; Spassieva, Stefka; Obeid, Lina M.; Birkbak, Nicolai Juul; Szallasi, Zoltan; McKnight, Nicole C.; Rowan, Andrew J.; Speirs, Valerie; Hanby, Andrew M.; Downward, Julian; Tooze, Sharon A.; Swanton, Charles.

    In: Journal of Pathology, Vol. 226, No. 3, 2012, p. 482-494.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  36. Published

    Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients. / Győrffy, Balázs; Lánczky, András; Szállási, Zoltán.

    In: Endocrine - Related Cancer, Vol. 19, No. 2, 2012, p. 197-208.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  37. Published

    Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing. / Gerlinger, Marco; Rowan, Andrew J.; Horswell, Stuart; Larkin, James; Endesfelder, David; Gronroos, Eva; Martinez, Pierre; Matthews, Nicholas; Stewart, Aengus; Tarpey, Patrick; Varela, Ignacio; Phillimore, Benjamin; Begum, Sharmin; McDonald, Neil Q.; Butler, Adam; Jones, David; Raine, Keiran; Latimer, Calli; Santos, Claudio R.; Nohadani, Mahrokh; Eklund, Aron Charles; Spencer-Dene, Bradley; Clark, Graham; Pickering, Lisa; Stamp, Gordon; Gore, Martin; Szallasi, Zoltan Imre; Downward, Julian; Futreal, P. Andrew; Swanton, Charles.

    In: New England Journal of Medicine, Vol. 366, No. 10, 2012, p. 883-892.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  38. Published

    Parallel Evolution under Chemotherapy Pressure in 29 Breast Cancer Cell Lines Results in Dissimilar Mechanisms of Resistance. / Tegze, Balint; Szallasi, Zoltan Imre; Haltrich, Iren; Penzvalto, Zsofia; Toth, Zsuzsa; Liko, Istvan; Gyoerffy, Balazs.

    In: P L o S One, Vol. 7, No. 2, 2012, p. e30804.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  39. Published

    Telomeric Allelic Imbalance Indicates Defective DNA Repair and Sensitivity to DNA-Damaging Agents. / Birkbak, Nicolai J.; Wang, Zhigang C.; Kim, Ji-Young; Eklund, Aron C.; Li, Qiyuan; Tian, Ruiyang; Bowman-Colin, Christian; Li, Yang; Greene-Colozzi, April; Iglehart, J. Dirk; Tung, Nadine; Ryan, Paula D.; Garber, Judy E.; Silver, Daniel P.; Szallasi, Zoltan; Richardson, Andrea L.

    In: Cancer Drug Discovery and Development, Vol. 2, No. 4, 2012, p. 366-375.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  40. 2011
  41. Published

    Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer. / Roylance, Rebecca; Endesfelder, David; Gorman, Patricia; Sander, Jil; Tomlinson, Ian; M. Hanby, Andrew; Speirs, Valerie; L. Richardson, Andrea; Birkbak, Nicolai Juul; Eklund, Aron Charles; Downward, Julian; Kschischo, Maik; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Cancer Epidemiology, Biomarkers & Prevention, 22.07.2011, p. 2184-2197.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  42. Published

    A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables.. / Endesfelder, David; McGranahan, Nicholas; Birkbak, Nicolai Juul; Szallasi, Zoltan Imre; Kschischo, Maik; A. Graham, Trevor; Swanton, Charles.

    In: OncoTarget, 2011.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  43. Published

    Chromosomal Instability Confers Intrinsic Multidrug Resistance. / Lee, Alvin J. X.; Endesfelder, David; Rowan, Andrew J.; Walther, Axel; Birkbak, Nicolai Juul; Futreal, P. Andrew; Downward, Julian; Szallasi, Zoltan Imre; Tomlinson, Ian P. M.; Howell, Michael; Kschischo, Maik; Swanton, Charles.

    In: Cancer Research, Vol. 71, No. 5, 2011, p. 1858-1870.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  44. Published

    Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response. / Li, Qiyuan; Eklund, Aron Charles; Birkbak, Nicolai Juul; Desmedt, Christine; Haibe-Kains, Benjamin; Sotiriou, Christos; Symmans, W. Fraser; Pusztai, Lajos; Brunak, Søren; Richardson, Andrea L; Szallasi, Zoltan Imre.

    In: B M C Bioinformatics, Vol. 12, No. 1, 2011, p. 310.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  45. Published

    Jetset: selecting the optimal microarray probe set to represent a gene. / Li, Qiyuan; Birkbak, Nicolai Juul; Gyorffy, Balazs; Szallasi, Zoltan Imre; Eklund, Aron Charles.

    In: B M C Bioinformatics, Vol. 12, No. 1, 2011, p. 474.

    Publication: Research - peer-reviewJournal article – Annual report year: 2012

  46. Published

    Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer. / Birkbak, Nicolai Juul; Eklund, Aron Charles; Li, Qiyuan; McClelland, Sarah E.; Endesfelder, David; Tan, Patrick; Tan, Iain B.; Richardson, Andrea L.; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Cancer Research, Vol. 71, No. 10, 2011, p. 3447-3452.

    Publication: Research - peer-reviewJournal article – Annual report year: 2011

  47. Published
  48. 2010
  49. Published

    A focused, PCR based gene expression signature to refine grade in breast cancer. / Szasz, A.; Tokes, A. M.; Szittya, L.; Baranyak, Z. S.; Szekely, B.; Eklund, Aron Charles; Li, Qiyuan; Swanton, C.; Szallasi, Zoltan Imre; Kulka, J.

    In: EJC SUPPLEMENTS, Vol. 8, No. 3, 2010, p. 226-226.

    Publication: ResearchConference abstract in journal – Annual report year: 2010

  50. Published

    Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer. / Szallasi, Zoltan Imre; Li, Yang; Zou, Lihua; Li, Qiyuan; Haibe-Kains, Benjamin; Tian, Ruiyang; Li, Yan; Desmedt, Christine; Sotiriou, Christos; Iglehart, J Dirk; Richardson, Andrea L; Wang, Zhigang Charles.

    In: Nature Medicine, Vol. 16, No. 2, 2010, p. 214-218.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  51. Published

    An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients. / Györffy, B; Lanczky, A; Eklund, Aron Charles; Denkert, Carsten; Budczies, J; Li, Qiyuan; Szallasi, Zoltan Imre.

    In: Breast Cancer Research and Treatment, Vol. 123, No. 3, 2010, p. 725-731.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  52. Published

    Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials. / Juul, Nicolai Stefan; Szallasi, Zoltan Imre; Eklund, Aron Charles; Li, Qiyuan; Burrell, RA; Gerlinger, M; Valero, V; Andreopoulou, E; Esteva, FJ; Symmans, WF; Desmedt, C; Haibe-Kains, B; Sotiriou, C; Pusztai, L; Swanton, C.

    In: Lancet Oncology, Vol. 11, No. 4, 2010, p. 358-365.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  53. Published

    Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer. / Szallasi, Zoltan Imre; Eklund, Aron Charles; Li, Qiyuan; Juul, Nicolai Stefan; Silver, Daniel P.; Richardson, Andrea L.; Wang, Zhigang C.; Leong, Chee-Onn; Calogrias, Diana; Buraimoh, Ayodele; Fatima, Aquila; Gelman, Rebecca S.; Ryan, Paula D.; Tung, Nadine M.; De Nicolo, Arcangela; Ganesan, Shridar; Miron, Alexander; Colin, Christian; Sgroi, Dennis C.; Ellisen, Leif W.; Winer, Eric P.; Garber, Judy E.

    In: Journal of Clinical Oncology, Vol. 28, No. 7, 2010, p. 1145-1153.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  54. Published

    Minimising Immunohistochemical False Negative ER Classification Using a Complementary 23 Gene Expression Signature of ER Status. / Li, Qiyuan; Eklund, Aron Charles; Birkbak, Nicolai Juul; Haibe-Kains, B.; Workman, Christopher; Richardson, A.L.; Szallasi, Zoltan Imre; Swanton, C.

    In: P L o S One, Vol. 5, No. 12, 2010.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  55. Published
  56. Published

    Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets. / Swanton, C.; Larkin, J.M.; Gerlinger, M.; Eklund, Aron Charles; Howell, M.; Stamp, G.; Downward, J.; Gore, M.; Futreal, P.A.; Escudier, B.; Andre, F.; Albiges, L.; Beuselinck, B.; Oudard, S.; Hoffmann, J.; Gyorffy, B.; Torrance, C.; Boehme, K.A.; Volkmer, H.; Toschi, L.; Nicke, B.; Beck, Marlene; Szallasi, Zoltan Imre.

    In: Genome Medicine, Vol. 2, No. 8, 2010.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  57. Published

    Targeting Chromosomal Instability and Tumour Heterogeneity in HER2-Positive Breast Cancer. / Burrell, Rebecca A.; Birkbak, Nicolai Juul; Johnston, Stephen R.; Reis-Filho, Jorge S.; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Journal of Cellular Biochemistry, Vol. 111, No. 4, 2010, p. 782-790.

    Publication: Research - peer-reviewJournal article – Annual report year: 2010

  58. 2009
  59. Published

    A Functional Metagene Incorporating TTK Protein Kinase, Aurora Kinase B and Glucosylceramide Synthase Predicts Response to Treatment in Primary Breast Cancer. / Juul, Nicolai Stefan; Eklund, Aron Charles; Li, Qiyuan; Downward, J.; Burrell, R.; Szallasi, Zoltan Imre; Swanton, C.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 602S-602S.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2009

  60. Published

    A Genomic-Profile Derived Summary Measure of Chromosomal Breakpoints Predicts Response to Treatment with the DNA-Damaging Agent Cisplatin.. / Juul, Nicolai Stefan; Wang, Y; Kim, JY; Eklund, Aron Charles; Li, Qiyuan; Carlton, VEH; Gerlinger, M; Swanton, C; Garber, JE; Silver, DP; Faham, M; Richardson, A. L; Szallasi, Zoltan Imre; Wang, Z. C.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 509S-510S.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2009

  61. Published

    Chromosomal instability determines taxane response. / Swanton, C.; Nicke, B.; Schuett, M.; Eklund, Aron Charles; Ng, C.; Li, Q.Y.; Hardcastle, T.; Lee, A.; Roy, R.; East, P.; Kschischo, M.; Endesfelder, D.; Wylie, P.; Kim, S. N.; Chen, J. G.; Howell, M.; Ried, T.; Habermann, J.K.; Auer, G.; Brenton, J. D.; Szallasi, Zoltan Imre; Downward, J.

    In: National Academy of Sciences. Proceedings, Vol. 106, No. 21, 2009, p. 8671-8676.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

  62. Published

    Computational Dissection of Tumor Expression Profiles. / Eklund, Aron Charles; Juul, Nicolai Stefan; Li, Qiyuan; Richardson, A. L; Szallasi, Zoltan Imre.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 591S-591S.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2009

  63. Published

    Consistent Principal Components from Triple Negative Breast Cancer Expression Profiles Yields Agent Specific Predictors of Chemotherapy Response. / Li, Qiyuan; Eklund, Aron Charles; Juul, Nicolai Stefan; Desmedt, C; Haibe-Kain, B; Sotiriou, C; Symmans, W. F.; Pusztai, L; Richardson, A. L.; Szallasi, Zoltan Imre.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 700S-700S.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2009

  64. Published

    Evaluation of Microarray Preprocessing Algorithms Based on Concordance with RT-PCR in Clinical Samples. / Hansen, Kasper Lage; Szallasi, Zoltan Imre; Eklund, Aron Charles; Gyorffy, B; Molnar, B.

    In: P L o S One, Vol. 4, No. 5, 2009, p. e5645.

    Publication: Research - peer-reviewJournal article – Annual report year: 2009

  65. Published
  66. Published

    Regulators of Mitotic Transition Determine Paclitaxel Resistance In Vitro and Predict Poor Prognosis in Breast Cancer In Vivo. / Burrell, R.A.; McClelland, S.E.; Juul, Nicolai Stefan; Downward, J.; Szallasi, Zoltan Imre; Swanton, C.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 641S-641S.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2009

  67. 2008
  68. Published
  69. Published

    Concordance of exon array and real-time PCR assessment of gene expression following cancer cell cytotoxic drug exposure. / Lee, A.J.X.; East, P.; Pepper, S.; Nicke, B.; Szallasi, Zoltan Imre; Eklund, Aron Charles; Downward, J.; Swanton, C.

    In: Cell Cycle, Vol. 7, No. 24, 2008, p. 3947-3948.

    Publication: Research - peer-reviewJournal article – Annual report year: 2008

  70. Published

    Correction of technical bias in clinical microarray data improves concordance with known biological information. / Eklund, Aron Charles; Szallasi, Zoltan Imre.

    In: Genome Biology, Vol. 9, No. 2, 2008, p. R26.

    Publication: Research - peer-reviewJournal article – Annual report year: 2008

  71. Published

    Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer. / Swanton, Charles; Szallasi, Zoltan Imre; Brenton, James D.; Downward, Julian.

    In: Breast Cancer Research (Online Edition), Vol. 10, No. 5, 2008, p. 214.

    Publication: Research - peer-reviewJournal article – Annual report year: 2008

  72. 2006
  73. Published

    A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. / Carter, SL; Eklund, AC; Kohane, IS; Harris, LN; Szallasi, Zoltan Imre.

    In: Nature Genetics, Vol. 38, 2006, p. 1043-1048.

    Publication: Research - peer-reviewJournal article – Annual report year: 2006

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