Zoltan Imre Szallasi

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  1. 2013
  2. Published

    31P gain of chromosomal region 15q26 cause increased expression of blm and fanci, and is associated with sensitivity to platinum chemotherapy in triple negative breast cancer. / Birkbak, Nicolai Juul; Li, Y.; Bowman-Collin, C.; Iglehart, J.D.; Silver, D.; Wang, Z.C.; Szallasi, Zoltan Imre; Richardson, A.

    In: Annals of Oncology, Vol. 24, No. suppl 3, 2013, p. iii22.

    Publication: Research - peer-review › Journal article – Annual report year: 2013

  3. Published

    45p deciphering patterns of chromosomal aberrations in breast cancer patients: how defects in specific dna repair genes affect the accumulation of gross dna aberrations in the cancer genome. / Marquard, Andrea Marion; Birkbak, Nicolai Juul; Eklund, Aron Charles; Varga, A.; Szüts, D.; Szallasi, Zoltan Imre.

    In: Annals of Oncology, Vol. 24, No. suppl 3, 2013, p. iii26.

    Publication: Research - peer-review › Journal article – Annual report year: 2013

  4. Published

    Prognostic and Predictive Markers in Metastatic Renal Cell Carcinoma. / Khattak, Muhammad A.; Bakr, Farrah; Krzystanek, Marcin; Szallasi, Zoltan Imre; Gerlinger, Marco; Santos, Claudio; Swanton, Charles; Pickering, Lisa M.; Gore, Martin E.; Larkin, James M.G.

    In: Journal of Clinical Oncology, Vol. 31, No. 7, 2013, p. 20971-972.

    Publication: Research - peer-review › Journal article – Annual report year: 2013

  5. 2012
  6. Published

    CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid‐specific cancer cell death through autophagy induction. / Lee, Alvin J. X.; Roylance, Rebecca; Sander, Jil; Gorman, Patricia; Endesfelder, David; Kschischo, Maik; Jones, Neil P.; East, Philip; Nicke, Barbara; Spassieva, Stefka; Obeid, Lina M.; Birkbak, Nicolai Juul; Szallasi, Zoltan; McKnight, Nicole C.; Rowan, Andrew J.; Speirs, Valerie; Hanby, Andrew M.; Downward, Julian; Tooze, Sharon A.; Swanton, Charles.

    In: Journal of Pathology, Vol. 226, No. 3, 2012, p. 482-494.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  7. Published

    Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients. / Győrffy, Balázs; Lánczky, András; Szállási, Zoltán.

    In: Endocrine - Related Cancer, Vol. 19, No. 2, 2012, p. 197-208.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  8. Published

    Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing. / Gerlinger, Marco; Rowan, Andrew J.; Horswell, Stuart; Larkin, James; Endesfelder, David; Gronroos, Eva; Martinez, Pierre; Matthews, Nicholas; Stewart, Aengus; Tarpey, Patrick; Varela, Ignacio; Phillimore, Benjamin; Begum, Sharmin; McDonald, Neil Q.; Butler, Adam; Jones, David; Raine, Keiran; Latimer, Calli; Santos, Claudio R.; Nohadani, Mahrokh; Eklund, Aron Charles; Spencer-Dene, Bradley; Clark, Graham; Pickering, Lisa; Stamp, Gordon; Gore, Martin; Szallasi, Zoltan Imre; Downward, Julian; Futreal, P. Andrew; Swanton, Charles.

    In: New England Journal of Medicine, Vol. 366, No. 10, 2012, p. 883-892.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  9. Published

    Methods for predicting anti-cancer response. / Szallasi, Zoltan Imre (Inventor); Eklund, Aron Charles (Inventor); Birkbak, Nicolai Juul (Inventor); Richardson, Andrea L. (Inventor); Silver, Daniel P. (Inventor); Wang, Zhigang (Inventor).

    IPC No.: C12Q1/68. Mar 01, 2012.

    Publication: Research › Patent – Annual report year: 2012

  10. Published

    Parallel Evolution under Chemotherapy Pressure in 29 Breast Cancer Cell Lines Results in Dissimilar Mechanisms of Resistance. / Tegze, Balint; Szallasi, Zoltan Imre; Haltrich, Iren; Penzvalto, Zsofia; Toth, Zsuzsa; Liko, Istvan; Gyoerffy, Balazs.

    In: P L o S One, Vol. 7, No. 2, 2012, p. e30804.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  11. Published

    Telomeric Allelic Imbalance Indicates Defective DNA Repair and Sensitivity to DNA-Damaging Agents. / Birkbak, Nicolai J.; Wang, Zhigang C.; Kim, Ji-Young; Eklund, Aron C.; Li, Qiyuan; Tian, Ruiyang; Bowman-Colin, Christian; Li, Yang; Greene-Colozzi, April; Iglehart, J. Dirk; Tung, Nadine; Ryan, Paula D.; Garber, Judy E.; Silver, Daniel P.; Szallasi, Zoltan; Richardson, Andrea L.

    In: Cancer Drug Discovery and Development, Vol. 2, No. 4, 2012, p. 366-375.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  12. 2011
  13. Published

    Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer. / Roylance, Rebecca; Endesfelder, David; Gorman, Patricia; Sander, Jil; Tomlinson, Ian; M. Hanby, Andrew; Speirs, Valerie; L. Richardson, Andrea; Birkbak, Nicolai Juul; Eklund, Aron Charles; Downward, Julian; Kschischo, Maik; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Cancer Epidemiology, Biomarkers & Prevention, 22.07.2011, p. 2184-2197.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  14. Published

    A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables.. / Endesfelder, David; McGranahan, Nicholas; Birkbak, Nicolai Juul; Szallasi, Zoltan Imre; Kschischo, Maik; A. Graham, Trevor; Swanton, Charles.

    In: OncoTarget, 2011.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  15. Published

    Chromosomal Instability Confers Intrinsic Multidrug Resistance. / Lee, Alvin J. X.; Endesfelder, David; Rowan, Andrew J.; Walther, Axel; Birkbak, Nicolai Juul; Futreal, P. Andrew; Downward, Julian; Szallasi, Zoltan Imre; Tomlinson, Ian P. M.; Howell, Michael; Kschischo, Maik; Swanton, Charles.

    In: Cancer Research, Vol. 71, No. 5, 2011, p. 1858-1870.

    Publication: Research - peer-review › Journal article – Annual report year: 2011

  16. Published

    Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response. / Li, Qiyuan; Eklund, Aron Charles; Birkbak, Nicolai Juul; Desmedt, Christine; Haibe-Kains, Benjamin; Sotiriou, Christos; Symmans, W. Fraser; Pusztai, Lajos; Brunak, Søren; Richardson, Andrea L; Szallasi, Zoltan Imre.

    In: B M C Bioinformatics, Vol. 12, No. 1, 2011, p. 310.

    Publication: Research - peer-review › Journal article – Annual report year: 2011

  17. Published

    Jetset: selecting the optimal microarray probe set to represent a gene. / Li, Qiyuan; Birkbak, Nicolai Juul; Gyorffy, Balazs; Szallasi, Zoltan Imre; Eklund, Aron Charles.

    In: B M C Bioinformatics, Vol. 12, No. 1, 2011, p. 474.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  18. Published

    Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer. / Birkbak, Nicolai Juul; Eklund, Aron Charles; Li, Qiyuan; McClelland, Sarah E.; Endesfelder, David; Tan, Patrick; Tan, Iain B.; Richardson, Andrea L.; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Cancer Research, Vol. 71, No. 10, 2011, p. 3447-3452.

    Publication: Research - peer-review › Journal article – Annual report year: 2011

  19. Published

    Parallel selection of chemotherapy-resistant cell lines to illuminate mechanisms of drug resistance in human tumors : Abstract of paper from the IMPAKT Breast Cancer Conference. / Krzystanek, Marcin; Eklund, Aron Charles; Birkbak, Nicolai Juul; Tegze, B.; Gautier, Laurent; Holberg Blicher, Lene; Swanton, C.; Richardson, A. L.; Gyorffy, B.; Szallasi, Zoltan Imre.

    In: ANNALS OF ONCOLOGY, Vol. 22, No. 2, 2011, p. ii44-ii47.

    Publication: Research - peer-review › Conference article – Annual report year: 2011

  20. 2010
  21. Published

    A focused, PCR based gene expression signature to refine grade in breast cancer. / Szasz, A.; Tokes, A. M.; Szittya, L.; Baranyak, Z. S.; Szekely, B.; Eklund, Aron Charles; Li, Qiyuan; Swanton, C.; Szallasi, Zoltan Imre; Kulka, J.

    In: EJC SUPPLEMENTS, Vol. 8, No. 3, 2010, p. 226-226.

    Publication: Research › Conference abstract in journal – Annual report year: 2010

  22. Published

    Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer. / Szallasi, Zoltan Imre; Li, Yang; Zou, Lihua; Li, Qiyuan; Haibe-Kains, Benjamin; Tian, Ruiyang; Li, Yan; Desmedt, Christine; Sotiriou, Christos; Iglehart, J Dirk; Richardson, Andrea L; Wang, Zhigang Charles.

    In: Nature Medicine, Vol. 16, No. 2, 2010, p. 214-218.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  23. Published

    An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients. / Györffy, B; Lanczky, A; Eklund, Aron Charles; Denkert, Carsten; Budczies, J; Li, Qiyuan; Szallasi, Zoltan Imre.

    In: Breast Cancer Research and Treatment, Vol. 123, No. 3, 2010, p. 725-731.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  24. Published

    Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials. / Juul, Nicolai Stefan; Szallasi, Zoltan Imre; Eklund, Aron Charles; Li, Qiyuan; Burrell, RA; Gerlinger, M; Valero, V; Andreopoulou, E; Esteva, FJ; Symmans, WF; Desmedt, C; Haibe-Kains, B; Sotiriou, C; Pusztai, L; Swanton, C.

    In: Lancet Oncology, Vol. 11, No. 4, 2010, p. 358-365.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  25. Published

    Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer. / Szallasi, Zoltan Imre; Eklund, Aron Charles; Li, Qiyuan; Juul, Nicolai Stefan; Silver, Daniel P.; Richardson, Andrea L.; Wang, Zhigang C.; Leong, Chee-Onn; Calogrias, Diana; Buraimoh, Ayodele; Fatima, Aquila; Gelman, Rebecca S.; Ryan, Paula D.; Tung, Nadine M.; De Nicolo, Arcangela; Ganesan, Shridar; Miron, Alexander; Colin, Christian; Sgroi, Dennis C.; Ellisen, Leif W.; Winer, Eric P.; Garber, Judy E.

    In: Journal of Clinical Oncology, Vol. 28, No. 7, 2010, p. 1145-1153.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  26. Published

    Minimising Immunohistochemical False Negative ER Classification Using a Complementary 23 Gene Expression Signature of ER Status. / Li, Qiyuan; Eklund, Aron Charles; Birkbak, Nicolai Juul; Haibe-Kains, B.; Workman, Christopher; Richardson, A.L.; Szallasi, Zoltan Imre; Swanton, C.

    In: P L o S One, Vol. 5, No. 12, 2010.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  27. Published

    Optimization of the BLASTN substitution matrix for prediction of non-specific DNA microarray hybridization. / Eklund, Aron Charles; Friis, Pia; Wernersson, Rasmus; Szallasi, Zoltan Imre.

    In: Nucleic Acids Research, Vol. 38, No. 4, 2010, p. e27.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  28. Published

    Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets. / Swanton, C.; Larkin, J.M.; Gerlinger, M.; Eklund, Aron Charles; Howell, M.; Stamp, G.; Downward, J.; Gore, M.; Futreal, P.A.; Escudier, B.; Andre, F.; Albiges, L.; Beuselinck, B.; Oudard, S.; Hoffmann, J.; Gyorffy, B.; Torrance, C.; Boehme, K.A.; Volkmer, H.; Toschi, L.; Nicke, B.; Beck, Marlene; Szallasi, Zoltan Imre.

    In: Genome Medicine, Vol. 2, No. 8, 2010.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  29. Published

    Targeting Chromosomal Instability and Tumour Heterogeneity in HER2-Positive Breast Cancer. / Burrell, Rebecca A.; Birkbak, Nicolai Juul; Johnston, Stephen R.; Reis-Filho, Jorge S.; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Journal of Cellular Biochemistry, Vol. 111, No. 4, 2010, p. 782-790.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  30. 2009
  31. Published

    A Functional Metagene Incorporating TTK Protein Kinase, Aurora Kinase B and Glucosylceramide Synthase Predicts Response to Treatment in Primary Breast Cancer. / Juul, Nicolai Stefan; Eklund, Aron Charles; Li, Qiyuan; Downward, J.; Burrell, R.; Szallasi, Zoltan Imre; Swanton, C.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 602S-602S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  32. Published

    A Genomic-Profile Derived Summary Measure of Chromosomal Breakpoints Predicts Response to Treatment with the DNA-Damaging Agent Cisplatin.. / Juul, Nicolai Stefan; Wang, Y; Kim, JY; Eklund, Aron Charles; Li, Qiyuan; Carlton, VEH; Gerlinger, M; Swanton, C; Garber, JE; Silver, DP; Faham, M; Richardson, A. L; Szallasi, Zoltan Imre; Wang, Z. C.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 509S-510S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  33. Published

    Chromosomal instability determines taxane response. / Swanton, C.; Nicke, B.; Schuett, M.; Eklund, Aron Charles; Ng, C.; Li, Q.Y.; Hardcastle, T.; Lee, A.; Roy, R.; East, P.; Kschischo, M.; Endesfelder, D.; Wylie, P.; Kim, S. N.; Chen, J. G.; Howell, M.; Ried, T.; Habermann, J.K.; Auer, G.; Brenton, J. D.; Szallasi, Zoltan Imre; Downward, J.

    In: National Academy of Sciences. Proceedings, Vol. 106, No. 21, 2009, p. 8671-8676.

    Publication: Research - peer-review › Journal article – Annual report year: 2009

  34. Published

    Computational Dissection of Tumor Expression Profiles. / Eklund, Aron Charles; Juul, Nicolai Stefan; Li, Qiyuan; Richardson, A. L; Szallasi, Zoltan Imre.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 591S-591S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  35. Published

    Consistent Principal Components from Triple Negative Breast Cancer Expression Profiles Yields Agent Specific Predictors of Chemotherapy Response. / Li, Qiyuan; Eklund, Aron Charles; Juul, Nicolai Stefan; Desmedt, C; Haibe-Kain, B; Sotiriou, C; Symmans, W. F.; Pusztai, L; Richardson, A. L.; Szallasi, Zoltan Imre.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 700S-700S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  36. Published

    Evaluation of Microarray Preprocessing Algorithms Based on Concordance with RT-PCR in Clinical Samples. / Hansen, Kasper Lage; Szallasi, Zoltan Imre; Eklund, Aron Charles; Gyorffy, B; Molnar, B.

    In: P L o S One, Vol. 4, No. 5, 2009, p. e5645.

    Publication: Research - peer-review › Journal article – Annual report year: 2009

  37. Published

    Paradoxical Relationship of Chromosomal Instability with Breast Cancer Outcome: Identification of a Good Prognostic ER Negative/HER2 Negative Breast Cancer Cohort with Extreme Chromosomal Instability. / Swanton, C.; Juul, Nicolai Stefan; Li, Q; Eklund, Aron Charles; Richardson, A; Szallasi, Zoltan Imre.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 656S-656S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  38. Published

    Regulators of Mitotic Transition Determine Paclitaxel Resistance In Vitro and Predict Poor Prognosis in Breast Cancer In Vivo. / Burrell, R.A.; McClelland, S.E.; Juul, Nicolai Stefan; Downward, J.; Szallasi, Zoltan Imre; Swanton, C.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 641S-641S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  39. 2008
  40. Published

    A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes. / Hansen, Kasper Lage; Hansen, Niclas Tue; Karlberg, Erik, Olof, Linnart; Eklund, Aron Charles; Roque, Francisco José Sousa Simões Almeida; Donahoe, P.K.; Szallasi, Zoltan Imre; Jensen, Thomas Skøt; Brunak, Søren.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 105, No. 52, 2008, p. 20870-20875.

    Publication: Research - peer-review › Journal article – Annual report year: 2008

  41. Published

    Concordance of exon array and real-time PCR assessment of gene expression following cancer cell cytotoxic drug exposure. / Lee, A.J.X.; East, P.; Pepper, S.; Nicke, B.; Szallasi, Zoltan Imre; Eklund, Aron Charles; Downward, J.; Swanton, C.

    In: Cell Cycle, Vol. 7, No. 24, 2008, p. 3947-3948.

    Publication: Research - peer-review › Journal article – Annual report year: 2008

  42. Published

    Correction of technical bias in clinical microarray data improves concordance with known biological information. / Eklund, Aron Charles; Szallasi, Zoltan Imre.

    In: Genome Biology, Vol. 9, No. 2, 2008, p. R26.

    Publication: Research - peer-review › Journal article – Annual report year: 2008

  43. Published

    Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer. / Swanton, Charles; Szallasi, Zoltan Imre; Brenton, James D.; Downward, Julian.

    In: Breast Cancer Research (Online Edition), Vol. 10, No. 5, 2008, p. 214.

    Publication: Research - peer-review › Journal article – Annual report year: 2008

  44. 2006
  45. Published

    A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. / Carter, SL; Eklund, AC; Kohane, IS; Harris, LN; Szallasi, Zoltan Imre.

    In: NATURE GENETICS, Vol. 38, 2006, p. 1043-1048.

    Publication: Research - peer-review › Journal article – Annual report year: 2006

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