Nicolai Juul Birkbak

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  1. 2013
  2. Published

    31P gain of chromosomal region 15q26 cause increased expression of blm and fanci, and is associated with sensitivity to platinum chemotherapy in triple negative breast cancer. / Birkbak, Nicolai Juul; Li, Y.; Bowman-Collin, C.; Iglehart, J.D.; Silver, D.; Wang, Z.C.; Szallasi, Zoltan Imre; Richardson, A.

    In: Annals of Oncology, Vol. 24, No. suppl 3, 2013, p. iii22.

    Publication: Research - peer-review › Journal article – Annual report year: 2013

  3. Published

    45p deciphering patterns of chromosomal aberrations in breast cancer patients: how defects in specific dna repair genes affect the accumulation of gross dna aberrations in the cancer genome. / Marquard, Andrea Marion; Birkbak, Nicolai Juul; Eklund, Aron Charles; Varga, A.; Szüts, D.; Szallasi, Zoltan Imre.

    In: Annals of Oncology, Vol. 24, No. suppl 3, 2013, p. iii26.

    Publication: Research - peer-review › Journal article – Annual report year: 2013

  4. 2012
  5. Published

    CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid‐specific cancer cell death through autophagy induction. / Lee, Alvin J. X.; Roylance, Rebecca; Sander, Jil; Gorman, Patricia; Endesfelder, David; Kschischo, Maik; Jones, Neil P.; East, Philip; Nicke, Barbara; Spassieva, Stefka; Obeid, Lina M.; Birkbak, Nicolai Juul; Szallasi, Zoltan; McKnight, Nicole C.; Rowan, Andrew J.; Speirs, Valerie; Hanby, Andrew M.; Downward, Julian; Tooze, Sharon A.; Swanton, Charles.

    In: Journal of Pathology, Vol. 226, No. 3, 2012, p. 482-494.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  6. Published

    Methods for predicting anti-cancer response. / Szallasi, Zoltan Imre (Inventor); Eklund, Aron Charles (Inventor); Birkbak, Nicolai Juul (Inventor); Richardson, Andrea L. (Inventor); Silver, Daniel P. (Inventor); Wang, Zhigang (Inventor).

    IPC No.: C12Q1/68. Mar 01, 2012.

    Publication: Research › Patent – Annual report year: 2012

  7. Published

    Profiles of Genomic Instability in High-Grade Serous Ovarian Cancer Predict Treatment Outcome. / Wang, Zhigang C.; Birkbak, Nicolai Juul; Culhane, Aedín C.; Drapkin, Ronny; Fatima, Aquila; Tian, Ruiyang; Schwede, Matthew; Alsop, Kathryn; Daniels, Kathryn E.; Piao, Huiying; Liu, Joyce; Etemadmoghadam, Dariush; Miron, Alexander; Salvesen, Helga B.; Mitchell, Gillian; DeFazio, Anna; Quackenbush, John; Berkowitz, Ross S.; Iglehart, J. Dirk; Bowtell, David D.L.; Matulonis, Ursula A.

    In: Clinical Cancer Research, Vol. 18, No. 20, 2012, p. 5806-5815.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  8. Published

    Telomeric Allelic Imbalance Indicates Defective DNA Repair and Sensitivity to DNA-Damaging Agents. / Birkbak, Nicolai J.; Wang, Zhigang C.; Kim, Ji-Young; Eklund, Aron C.; Li, Qiyuan; Tian, Ruiyang; Bowman-Colin, Christian; Li, Yang; Greene-Colozzi, April; Iglehart, J. Dirk; Tung, Nadine; Ryan, Paula D.; Garber, Judy E.; Silver, Daniel P.; Szallasi, Zoltan; Richardson, Andrea L.

    In: Cancer Drug Discovery and Development, Vol. 2, No. 4, 2012, p. 366-375.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  9. 2011
  10. Published

    Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer. / Roylance, Rebecca; Endesfelder, David; Gorman, Patricia; Sander, Jil; Tomlinson, Ian; M. Hanby, Andrew; Speirs, Valerie; L. Richardson, Andrea; Birkbak, Nicolai Juul; Eklund, Aron Charles; Downward, Julian; Kschischo, Maik; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Cancer Epidemiology, Biomarkers & Prevention, 22.07.2011, p. 2184-2197.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  11. Published

    A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables.. / Endesfelder, David; McGranahan, Nicholas; Birkbak, Nicolai Juul; Szallasi, Zoltan Imre; Kschischo, Maik; A. Graham, Trevor; Swanton, Charles.

    In: OncoTarget, 2011.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  12. Published

    Chromosomal Instability Confers Intrinsic Multidrug Resistance. / Lee, Alvin J. X.; Endesfelder, David; Rowan, Andrew J.; Walther, Axel; Birkbak, Nicolai Juul; Futreal, P. Andrew; Downward, Julian; Szallasi, Zoltan Imre; Tomlinson, Ian P. M.; Howell, Michael; Kschischo, Maik; Swanton, Charles.

    In: Cancer Research, Vol. 71, No. 5, 2011, p. 1858-1870.

    Publication: Research - peer-review › Journal article – Annual report year: 2011

  13. Published

    Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response. / Li, Qiyuan; Eklund, Aron Charles; Birkbak, Nicolai Juul; Desmedt, Christine; Haibe-Kains, Benjamin; Sotiriou, Christos; Symmans, W. Fraser; Pusztai, Lajos; Brunak, Søren; Richardson, Andrea L; Szallasi, Zoltan Imre.

    In: B M C Bioinformatics, Vol. 12, No. 1, 2011, p. 310.

    Publication: Research - peer-review › Journal article – Annual report year: 2011

  14. Published

    Jetset: selecting the optimal microarray probe set to represent a gene. / Li, Qiyuan; Birkbak, Nicolai Juul; Gyorffy, Balazs; Szallasi, Zoltan Imre; Eklund, Aron Charles.

    In: B M C Bioinformatics, Vol. 12, No. 1, 2011, p. 474.

    Publication: Research - peer-review › Journal article – Annual report year: 2012

  15. Published

    Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer. / Birkbak, Nicolai Juul; Eklund, Aron Charles; Li, Qiyuan; McClelland, Sarah E.; Endesfelder, David; Tan, Patrick; Tan, Iain B.; Richardson, Andrea L.; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Cancer Research, Vol. 71, No. 10, 2011, p. 3447-3452.

    Publication: Research - peer-review › Journal article – Annual report year: 2011

  16. Published

    Parallel selection of chemotherapy-resistant cell lines to illuminate mechanisms of drug resistance in human tumors : Abstract of paper from the IMPAKT Breast Cancer Conference. / Krzystanek, Marcin; Eklund, Aron Charles; Birkbak, Nicolai Juul; Tegze, B.; Gautier, Laurent; Holberg Blicher, Lene; Swanton, C.; Richardson, A. L.; Gyorffy, B.; Szallasi, Zoltan Imre.

    In: ANNALS OF ONCOLOGY, Vol. 22, No. 2, 2011, p. ii44-ii47.

    Publication: Research - peer-review › Conference article – Annual report year: 2011

  17. 2010
  18. Published

    AMOUNT OF ALLELIC IMBALANCE PREDICTS RESPONSE TO CISPLATIN IN BREAST AND OVARIAN CANCER. / Birkbak, Nicolai Juul; Wang, Z.C.; Li, Y.; Wang, Y.; Carlton, V.; Iglehart, J.D.; Garber, J.E.; Silver, D.P.; Szallasi, Z.; Richardson, A.L.

    In: Annals of Oncology, Vol. 21, No. 30-30, 2010, p. 33P.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2010

  19. Published

    Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials. / Juul, Nicolai Stefan; Szallasi, Zoltan Imre; Eklund, Aron Charles; Li, Qiyuan; Burrell, RA; Gerlinger, M; Valero, V; Andreopoulou, E; Esteva, FJ; Symmans, WF; Desmedt, C; Haibe-Kains, B; Sotiriou, C; Pusztai, L; Swanton, C.

    In: Lancet Oncology, Vol. 11, No. 4, 2010, p. 358-365.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  20. Published

    Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer. / Szallasi, Zoltan Imre; Eklund, Aron Charles; Li, Qiyuan; Juul, Nicolai Stefan; Silver, Daniel P.; Richardson, Andrea L.; Wang, Zhigang C.; Leong, Chee-Onn; Calogrias, Diana; Buraimoh, Ayodele; Fatima, Aquila; Gelman, Rebecca S.; Ryan, Paula D.; Tung, Nadine M.; De Nicolo, Arcangela; Ganesan, Shridar; Miron, Alexander; Colin, Christian; Sgroi, Dennis C.; Ellisen, Leif W.; Winer, Eric P.; Garber, Judy E.

    In: Journal of Clinical Oncology, Vol. 28, No. 7, 2010, p. 1145-1153.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  21. Published

    Minimising Immunohistochemical False Negative ER Classification Using a Complementary 23 Gene Expression Signature of ER Status. / Li, Qiyuan; Eklund, Aron Charles; Birkbak, Nicolai Juul; Haibe-Kains, B.; Workman, Christopher; Richardson, A.L.; Szallasi, Zoltan Imre; Swanton, C.

    In: P L o S One, Vol. 5, No. 12, 2010.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  22. Published

    Targeting Chromosomal Instability and Tumour Heterogeneity in HER2-Positive Breast Cancer. / Burrell, Rebecca A.; Birkbak, Nicolai Juul; Johnston, Stephen R.; Reis-Filho, Jorge S.; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Journal of Cellular Biochemistry, Vol. 111, No. 4, 2010, p. 782-790.

    Publication: Research - peer-review › Journal article – Annual report year: 2010

  23. 2009
  24. Published

    A Functional Metagene Incorporating TTK Protein Kinase, Aurora Kinase B and Glucosylceramide Synthase Predicts Response to Treatment in Primary Breast Cancer. / Juul, Nicolai Stefan; Eklund, Aron Charles; Li, Qiyuan; Downward, J.; Burrell, R.; Szallasi, Zoltan Imre; Swanton, C.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 602S-602S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  25. Published

    A Genomic-Profile Derived Summary Measure of Chromosomal Breakpoints Predicts Response to Treatment with the DNA-Damaging Agent Cisplatin.. / Juul, Nicolai Stefan; Wang, Y; Kim, JY; Eklund, Aron Charles; Li, Qiyuan; Carlton, VEH; Gerlinger, M; Swanton, C; Garber, JE; Silver, DP; Faham, M; Richardson, A. L; Szallasi, Zoltan Imre; Wang, Z. C.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 509S-510S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  26. Published

    Computational Dissection of Tumor Expression Profiles. / Eklund, Aron Charles; Juul, Nicolai Stefan; Li, Qiyuan; Richardson, A. L; Szallasi, Zoltan Imre.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 591S-591S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  27. Published

    Consistent Principal Components from Triple Negative Breast Cancer Expression Profiles Yields Agent Specific Predictors of Chemotherapy Response. / Li, Qiyuan; Eklund, Aron Charles; Juul, Nicolai Stefan; Desmedt, C; Haibe-Kain, B; Sotiriou, C; Symmans, W. F.; Pusztai, L; Richardson, A. L.; Szallasi, Zoltan Imre.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 700S-700S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  28. Published

    Paradoxical Relationship of Chromosomal Instability with Breast Cancer Outcome: Identification of a Good Prognostic ER Negative/HER2 Negative Breast Cancer Cohort with Extreme Chromosomal Instability. / Swanton, C.; Juul, Nicolai Stefan; Li, Q; Eklund, Aron Charles; Richardson, A; Szallasi, Zoltan Imre.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 656S-656S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

  29. Published

    Regulators of Mitotic Transition Determine Paclitaxel Resistance In Vitro and Predict Poor Prognosis in Breast Cancer In Vivo. / Burrell, R.A.; McClelland, S.E.; Juul, Nicolai Stefan; Downward, J.; Szallasi, Zoltan Imre; Swanton, C.

    In: Cancer Research, Vol. 69, No. 24, 2009, p. 641S-641S.

    Publication: Research - peer-review › Conference abstract in journal – Annual report year: 2009

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