Nicolai Juul Birkbak

  1. Published

    MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy. / Neupane, Manish; Clark, Allison P.; Landini, Serena; Birkbak, Nicolai Juul; Eklund, Aron Charles; Lim, Elgene; Culhane, Aedin C.; Barry, William T.; Schumacher, Steven E.; Beroukhim, Rameen; Szallasi, Zoltan Imre; Vidal, Marc; Hill, David E.; Silver, Daniel P.

    In: Cancer Discovery, Vol. 6, No. 1, 2016, p. 45-58.

    Publication: Research - peer-reviewJournal article – Annual report year: 2016

  2. Published

    Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome. / Favero, Francesco; McGranahan, Nicholas; Salm, Maximilian P.; Birkbak, Nicolai Juul; Sanborn, J. Zachary ; Benz, Stephen C. ; Becq, Jennifer; Peden, John F. ; Kingsbury, Zoya ; Grocok, Russell J. ; Eklund, Aron Charles.

    In: Annals of Oncology, Vol. 26, No. 5, 2015, p. 880-887.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  3. Published
  4. Published

    SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. / Kanu, N.; Grönroos, E.; Martinez, P.; Burrell, R. A.; Yi Goh, X.; Bartkova, J.; Maya-Mendoza, A.; Mistrík, M.; Rowan, A. J.; Patel, H.; Rabinowitz, A.; East, P.; Wilson, G.; Santos, C. R.; McGranahan, N.; Gulati, S.; Gerlinger, M.; Birkbak, Nicolai Juul; Joshi, Tejal; Alexandrov, L. B.; Stratton, M. R.; Powles, T.; Matthews, N.; Bates, P. A.; Stewart, A.; Szallasi, Zoltan Imre; Larkin, J.; Bartek, J.; Swanton, C.

    In: Oncogene, Vol. 34, 2015, p. 5699-5708.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  5. Published
  6. Published

    TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen. / Marquard, Andrea Marion; Birkbak, Nicolai Juul; Thomas, Cecilia Engel; Favero, Francesco; Krzystanek, Marcin; Lefebvre, Celine; Ferté, Charles; Jamal-Hanjani, Mariam; Wilson, Gareth A.; Shafi, Seema; Swanton, Charles; André, Fabrice; Szallasi, Zoltan Imre; Eklund, Aron Charles.

    In: BMC Medical Genomics, Vol. 8, No. 58, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  7. Published

    Clonal status of actionable driver events and the timing of mutational processes in cancer evolution. / McGranahan, Nicholas; Favero, Francesco; de Bruin, Elza C.; Birkbak, Nicolai Juul; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Science Translational Medicine, Vol. 7, No. 283, 283ra54, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  8. Published

    Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection. / Christensen, Dan Ploug; Gysemans, Conny; Lundh, Morten; Dahllöf, Mattias Salling; Noesgaard, Daniel; Schmidt, Søren Fisker; Mandrup, Susanne; Birkbak, Nicolai Juul; Workman, Christopher; Piemonti, Lorenzo; Blaabjerg, Lykke; Monzani, Valmen; Fossati, Gianluca; Mascagni, Paolo; Paraskevas, Steven; Aikin, Reid A.; Billestrup, Nils; Grunnet, Lars Groth; Dinarello, Charles A.; Mathieu, Chantal; Mandrup-Poulsen, Thomas.

    In: National Academy of Sciences. Proceedings, Vol. 111, No. 3, 2014, p. 1055-1059.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  9. Published

    Systematic Evaluation of the Prognostic Impact and Intratumour Heterogeneity of Clear Cell Renal Cell Carcinoma Biomarkers. / Gulati, Sakshi; Martinez, Pierre; Joshi, Tejal; Birkbak, Nicolai Juul; Santos, Claudio R.; Rowan, Andrew J.; Pickering, Lisa; Gore, Martin; Larkin, James; Szallasi, Zoltan Imre; Bates, Paul A.; Swanton, Charles; Gerlinger, Marco.

    In: European Urology, Vol. 66, No. 5, 2014, p. 936-948.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  10. Published

    Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study. / Jamal-Hanjani, Mariam; Hackshaw, Alan; Ngai, Yenting; Shaw, Jacqueline; Dive, Caroline; Quezada, Sergio; Middleton, Gary; de Bruin, Elza; Le Quesne, John; Shafi, Seema; Falzon, Mary; Horswell, Stuart; Blackhall, Fiona; Khan, Iftekhar; Janes, Sam; Nicolson, Marianne; Lawrence, David; Forster, Martin; Fennell, Dean; Lee, Siow-Ming; Lester, Jason; Kerr, Keith; Muller, Salli; Iles, Natasha; Smith, Sean; Murugaesu, Nirupa; Mitter, Richard; Salm, Max; Stuart, Aengus; Matthews, Nik; Adams, Haydn; Ahmad, Tanya; Attanoos, Richard; Bennett, Jonathan; Birkbak, Nicolai Juul; Booton, Richard; Brady, Ged; Buchan, Keith; Capitano, Arrigo; Chetty, Mahendran; Cobbold, Mark; Crosbie, Philip; Davies, Helen; Denison, Alan; Djearman, Madhav; Goldman, Jacki; Haswell, Tom; Joseph, Leena; Kornaszewska, Malgorzata; Krebs, Matthew; Langman, Gerald; MacKenzie, Mairead; Millar, Joy; Morgan, Bruno; Naidu, Babu; Nonaka, Daisuke; Peggs, Karl; Pritchard, Catrin; Remmen, Hardy; Rowan, Andrew; Shah, Rajesh; Smith, Elaine; Summers, Yvonne; Taylor, Magali; Veeriah, Selvaraju; Waller, David; Wilcox, Ben; Wilcox, Maggie; Woolhouse, Ian; McGranahan, Nicholas; Swanton, Charles.

    In: P L o S Biology, Vol. 12, No. 7, e1001906, 2014.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

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