Nicolai Juul Birkbak

  1. 2016
  2. Published

    MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy. / Neupane, Manish; Clark, Allison P.; Landini, Serena; Birkbak, Nicolai Juul; Eklund, Aron Charles; Lim, Elgene; Culhane, Aedin C.; Barry, William T.; Schumacher, Steven E.; Beroukhim, Rameen; Szallasi, Zoltan Imre; Vidal, Marc; Hill, David E.; Silver, Daniel P.

    In: Cancer Discovery, Vol. 6, No. 1, 2016, p. 45-58.

    Publication: Research - peer-reviewJournal article – Annual report year: 2016

  3. 2015
  4. Published

    Clonal status of actionable driver events and the timing of mutational processes in cancer evolution. / McGranahan, Nicholas; Favero, Francesco; de Bruin, Elza C.; Birkbak, Nicolai Juul; Szallasi, Zoltan Imre; Swanton, Charles.

    In: Science Translational Medicine, Vol. 7, No. 283, 283ra54, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  5. Published

    Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome. / Favero, Francesco; McGranahan, Nicholas; Salm, Maximilian P.; Birkbak, Nicolai Juul; Sanborn, J. Zachary ; Benz, Stephen C. ; Becq, Jennifer; Peden, John F. ; Kingsbury, Zoya ; Grocok, Russell J. ; Eklund, Aron Charles.

    In: Annals of Oncology, Vol. 26, No. 5, 2015, p. 880-887.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  6. Published
  7. Published
  8. Published

    SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. / Kanu, N.; Grönroos, E.; Martinez, P.; Burrell, R. A.; Yi Goh, X.; Bartkova, J.; Maya-Mendoza, A.; Mistrík, M.; Rowan, A. J.; Patel, H.; Rabinowitz, A.; East, P.; Wilson, G.; Santos, C. R.; McGranahan, N.; Gulati, S.; Gerlinger, M.; Birkbak, Nicolai Juul; Joshi, Tejal; Alexandrov, L. B.; Stratton, M. R.; Powles, T.; Matthews, N.; Bates, P. A.; Stewart, A.; Szallasi, Zoltan Imre; Larkin, J.; Bartek, J.; Swanton, C.

    In: Oncogene, Vol. 34, 2015, p. 5699-5708.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  9. Published

    TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen. / Marquard, Andrea Marion; Birkbak, Nicolai Juul; Thomas, Cecilia Engel; Favero, Francesco; Krzystanek, Marcin; Lefebvre, Celine; Ferté, Charles; Jamal-Hanjani, Mariam; Wilson, Gareth A.; Shafi, Seema; Swanton, Charles; André, Fabrice; Szallasi, Zoltan Imre; Eklund, Aron Charles.

    In: BMC Medical Genomics, Vol. 8, No. 58, 2015.

    Publication: Research - peer-reviewJournal article – Annual report year: 2015

  10. 2014
  11. Published

    A pan-cancer analysis of inferred homologous recombination deficiency identifies potential platinum benefit in novel subtypes. / Marquard, Andrea Marion; Eklund, Aron Charles; Wang, Zhigang C.; Richardson, Andrea L.; Szallasi, Zoltan Imre; Birkbak, Nicolai Juul.

    In: Cancer Research, Vol. 74, No. 19 - Supplement, 2822, 2014.

    Publication: Research - peer-reviewConference abstract in journal – Annual report year: 2015

  12. Published

    Enhancing Reproducibility in Cancer Drug Screening: How Do We Move Forward? / Shi, Leming; Haibe-Kains, Benjamin; Birkbak, Nicolai Juul; Bedard, Philippe L.; Hatzis, Christos; Stern, David F.; Clarke, Robert; Quackenbush, John; Beck, Andrew H.; Aerts, Hugo J. W. L.

    In: Cancer Research, Vol. 74, No. 15, 2014, p. 4016-4023.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

  13. Published

    Expression of regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in primary breast cancer. / Roylance, Rebecca; Endesfelder, David; Jamal-Hanjani, Mariam; Burrell, Rebecca A.; Gorman, Patricia; Sander, Jil; Murphy, Niamh; Birkbak, Nicolai Juul; Hanby, Andrew M.; Speirs, Valerie; Johnston, Stephen R. D.; Kschischo, Maik; Swanton, Charles.

    In: Breast Cancer Research and Treatment, Vol. 148, No. 1, 2014, p. 221-229.

    Publication: Research - peer-reviewJournal article – Annual report year: 2014

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